Immuno-Oncology, 1st ed. 2020 Cellular and Translational Approaches Methods in Pharmacology and Toxicology Series

An In Vitro System Combining Tumor Cells and Lymphocytes to Predict the In Vivo Response of Immunomodulatory Antibodies.- High-Throughput Direct Cell Counting Method for Immuno-Oncology Functional Assays Using Image Cytometry.- In Vitro Immunotherapy Potency Assays Using Real-Time Cell Analysis.- Assessing the Potency of T Cell-Redirecting Therapeutics Using In Vitro Cancer Cell Killing Assays.- Induction and Potential Reversal of a T Cell Exhaustion-Like State:In Vitro Potency Assay for Functional Screening of Immune Checkpoint Drug Candidates.- Validation of an Image-Based 3D Natural Killer Cell-Mediated Cytotoxicity Assay.- 3D-3-Culture: Tumor Models to Study Heterotypic Interactions in the Tumor Microenvironment.- Considerations in Developing Reporter Gene Bioassays for Biologics.- Miniaturized Single Cell Imaging for Developing Immuno-Oncology Combinational Therapies.- Precision Medicine: The Function of Receptor Occupancy in Drug Development.- In Vitro Assays for Assessing Potential Adverse Effects of Cancer Immunotherapeutics.- The Quest for the Next-Generation of Tumor Targets: Discovery and Prioritization in the Genomics Era.