Chemistry of Thioamides, 1st ed. 2019
Coordonnateur : Murai Toshiaki
This book covers whole aspects of the sulfur isologues of amides. Starting from the synthetic methods of thioamides, a range of synthetic applications to the construction of carbon?sulfur and carbon?carbon bonds, to asymmetric reactions, to formation of heterocycles are described.
Among the array of thiocarbonyl compounds, thioamides are readily handled in room temperature air. Some of their characteristic features are that the polarity of C=S bonds in thioamides is much smaller than C=O bonds in ordinary amides, that thioamides possess higher HOMO and lower LUMO when compared with those of ordinary amides, and that carbon atoms alpha to the C=S and nitrogen atoms in thioamides are more acidic than those in ordinary amides. Theoretical studies further disclose their features.
Thioamides are also used as ligands to a wide variety of metals. Their unique photophysical properties and catalytic activities are described here. Characteristic features of biologicallyrelevant thioamides, e.g., thiopeptides and related compounds, are the final focus of the book.
1. Thioamides : Overview.- 2. Theoretical Aspects of Thioamides.- 3. Synthesis of Thioamides.- 4. Reaction of Thioamides.- 5. Asymmetric Synthesis Using Thioamides.- 6. Synthesis of Heterocycles from Thioamides.- 7.Thioamides-based Transition Metal-complexes.- 8. Thioamide-containing Peptides and Proteins.
He has been a Section Editor of the Chemistry Letters since 2013 and one of Editorial Advisory Board Members of ChemistryOpen since 2017.
He was awarded Progress Award in Synthetic Organic Chemistry, Japan (1997, 2) and Gifu Shinbun Grand Prize (2017.2).
His research interest is Synthetic Organic and Elements Chemistry Related to Organochalcogen and Organophosphorus Compounds.
Date de parution : 08-2020
Ouvrage de 238 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 105,49 €
Ajouter au panierDate de parution : 05-2019
Ouvrage de 238 p.
15.5x23.5 cm