Uveitis, Softcover reprint of the original 1st ed. 1995 A Clinical Manual for Ocular Inflammation

As a garden is to a gardener, so a book is to its author. Nurtured out of love, both are a source of pride and hope. Microbiology, immunol­ ogy, infectious diseases, rheumatology, and ophthalmology are the seeds of this textbook on uveitis. Over the years, these branches of medicine have been cultivated and garnered to care for patients with inflammatory diseases of the eye, a most hardy species in the family of ocular maladies. The aim of this clinical manual is to give both a serviceable frame­ work and practical information on ocular inflammatory disease. The first section is devoted to general principles and commonly held sup­ positions in the field of uveitis. A system of diagnosis, based on the differential, is also offered. Traumatic uveitis is addressed in the sec­ ond section. The third part examines infectious diseases that have been identified with uveitis. These are frequently curable forms of ocular inflammation caused by replicating foreign antigens. The fourth section of this textbook considers inflammatory diseases of the eye with a presumed autoimmune mechanism. A disobedient, autoreactive immune response is postulated to playa role in these forms of uveitis. Masquerade and idiopathic conditions are dis­ cussed in the final chapters. Etiology, epidemiology, pathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, and prognosis are provided for each disease syndrome. As with most gardens, there are many styles and delightful entrances to the field of uveitis.

General Principles.- 1 Introduction.- General Information.- Definitions.- Epidemiology.- Pathology/Pathophysiology.- Classification.- Etiology and Diagnostic Considerations.- 2 Symptoms and Signs of Uveitis.- Symptoms.- Signs.- 3 Clinical Approach to the Patient with Ocular Inflammation.- Methods of Diagnosis in Uveitis.- Differential-Based Diagnostic System.- 4 Laboratory Testing.- Routine and Frequently Ordered Tests.- Tests Individualized for the Differential Diagnosis.- Special Blood Tests.- Radiologic Testing.- Fluorescein Angiography.- Ultrasonography.- Tissue Biopsy.- 5 Medical Therapy for Uveitis.- General Principles.- Nonspecific Therapy—General Considerations.- Specific Therapy—General Considerations.- Topical Medical Therapy for Uveitis.- Regional Medical Therapy for Uveitis.- Systemic Medical Therapy for Uveitis.- 6 Surgical Treatments in Uveitis.- General Information.- Surgical Challenges in the Patient with Uveitis.- Surgical Procedures and Considerations in Uveitis.- Ocular Inflammation Associated with Trauma.- 7 Traumatic Uveitis.- Nonsurgical Trauma.- Surgical Trauma and Postoperative Inflammation.- Ocular Inflammation Associated with Infectious Diseases.- 8 Viral Diseases.- Viral Diseases Associated with Keratouveitis.- Viral Diseases Associated with Retinitis and Uveitis.- Acute Retinal Necrosis Syndrome.- Ocular Manifestations of Infection with HIV and AIDS.- Cytomegalovirus Retinitis.- 9 Bacterial Diseases.- Treponema pallidum—Syphilis.- Borrelia burgdorferi—Lyme Disease.- Leptospira species—Leptospirosis.- Mycobacterium tuberculi—Tuberculosis.- Mycobacterium leprae—Leprosy.- Brucella species—Brucellosis.- Whipple’s Disease.- 10 Fungal Diseases.- Histoplasmosis.- Candidiasis.- Coccidiomycosis.- Sporotrichosis.- Cryptococcosis.- 11 Protozoal Diseases.- Toxoplasmosis.- Amoebiasis.- Trypanosomiasis.- Giardiasis.- Pneumocystosis.- 12 Helminthic Diseases.- Toxocariasis.- Ascariasis.- Onchocerciasis.- Loiasis.- Cysticercosis.- Diffuse Unilateral Subacute Neuroretinitis.- 13 Insect Disease.- Ophthalmomyiasis.- 14 Animal Disease.- Ophthalmia Nodosa.- Ocular Inflammation Associated with Immunologic Diseases.- 15 Type I Hypersensitivity.- Hay Fever.- Atopie Keratoconjunctivitis.- Vernal Keratoconjunctivitis.- 16 Type II Hypersensitivity.- Cicatricial Pemphigoid.- Lens-Induced Uveitis.- 17 Type III Hypersensitivity.- Ankylosing Spondylitis.- Behcet’s Disease.- Chürg-Strauss Syndrome.- Cogan’s Syndrome.- Dermatomyositis and Polymyositis.- Erythema Multiforme (Stevens-Johnson Syndrome).- Inflammatory Bowel Disease.- Juvenile Rheumatoid Arthritis.- Psoriatic Arthritis.- Reiter’s Syndrome.- Relapsing Polychondritis.- Rheumatoid Arthritis.- Polyarteritis Nodosa.- Systemic Sclerosis With or Without Scleroderma.- Sjögren’s Syndrome.- Systemic Lupus Erythematosus.- Temporal Arteritis or Giant Cell Arteritis.- Wegener’s Granulomatosis.- 18 Type IV Hypersensitivity.- Skin Disorders.- Sclera/Conjunctiva/Cornea.- Iris and Ciliary Body.- Vitreous Disorders.- Retina.- Choroid.- Sarcoidosis.- Ocular Inflammations Associated with Masquerade Syndromes.- 19 Neoplastic and Infectious Diseases Masquerading as Uveitis.- Intraocular Lymphoma (Reticulum Cell Sarcoma).- Infectious Endophthalmitis.- Chronic Anaerobic Endophthalmitis.