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The Immune System and Mental Health

Langue : Anglais

Auteurs :

Couverture de l’ouvrage The Immune System and Mental Health

The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry.

Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson?s and Alzheimer?s-like dementia are explored.

1. Multiple Pathways Linked to Mental Health and Illness 2. The Immune System: An Overview 3. Bacteria, Viruses, and the Microbiome 4. Life-Style Factors Affecting Biological Processes and Health 5. Stressor Processes and Effects on Neurobiological Functioning 6. Stress and Immunity 7. Prenatal and Early Postnatal Influences on Health 8. Depressive Disorders 9. Anxiety Disorders 10. Posttraumatic Stress Disorder 11. Pain Processes 12. Autism 13. Schizophrenia 14. Inflammatory Roads to Parkinson’s Disease 15. A Neuroinflammatory View of Alzheimer’s Disease 16. Comorbidities in Relation to Inflammatory processes

Advanced students and researchers in neuroscience, neuroimmunology, neuropsychiatry, neuropsychology, the behavioral and social sciences, and immunology

Hymie Anisman received his PhD from the University of Waterloo, where he was also on faculty for two years, and has been a Professor at Carleton University, since 1994. He has also held an adjunct appointment with the Institute of Mental Health Research (Royal Ottawa Hospital) since 1993. Professor Anisman was a Senior Ontario Mental Health Research Fellow, is a Fellow of the Royal Society of Canada, and held a Canada Research Chair in Neuroscience from 2001-2015, and has since held the position of Canada Research Professor. The principle theme of his research has concerned the influence of stressors on neurochemical, neuroendocrine and immune systems, and how these influence psychological (anxiety, depression) and physical illnesses including neurodegenerative, heart disease, and cancer progression.
Shawn Hayley is a Full Professor and previous Canada Research Chair in the Department of Neuroscience at Carleton University. Some of his research examines how the immune system influences neuroplasticity of the brain and consequently, how could be important for the development of new antidepressant drugs. As well, Dr. Hayley has been focused on how inflammation within the brain can cause neuronal degeneration and contribute to the onset and progression of Parkinson’s disease. The Hayley lab is involved in studies in assessing how chemical (e.g. pesticides) immunologic (e.g. viral, bacterial agents) and even psychological environmental stressors can contribute to the development of Parkinson's disease, as well as it comorbid states (e.g. depression, anxiety). Much of this research is focused on how the brain's specialized immune cells, the microglia, are involved in the generation of neuronal pathology, as well as possibly recovery from pathology.
Alex Kusnecov received his doctorate from the University of Newcastle, New South Wales, Australia, after which he conducted postdoctoral research in psychoneuroimmunology at the University of Rochester. Subsequently, he
  • Considers both basic human and animal studies that address immunological changes relating to mental health problems across the lifespan
  • Incorporates techniques, concepts and ideas from a variety of social, behavioral and life sciences
  • Explores the relatively new area of the microbiome and how the microbial composition of the gut influences brain function and mental health

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