Genomic and Molecular Cardiovascular Medicine Genomic and Precision Medicine in Clinical Practice Series
Coordonnateurs : Kumar Dhavendra, Wilde Arthur A.M., Elliott Perry Mark
The Genomic and Molecular Cardiovascular Medicine largely focuses on pertinent genomic and molecular aspects of cardiovascular medicine relevant to all levels of clinical practice, from primary care to preventive healthcare. The book also focuses on practice applications of translational genomic and molecular developments and advances that impact on cardiovascular system structure and function. Each chapter is evidence-based and comprehensive, with in-depth, cutting-edge knowledge relevant to the practice of clinical cardiology and cardiovascular surgery. The book aims to fill a major gap of knowledge resource focused on genomic and molecular aspects of contemporary cardiovascular medicine and surgery practice.
In view of scientific and technical complexities of the field, the book is written by a team of globally acknowledged experts in respective clinical, investigative, therapeutic and preventive aspects. The current practices within cardiovascular medicine and surgery offer excellent opportunity for genomic and molecular applications to achieve the high order effectiveness with maximum efficiency.
2. Methods in genomic and molecular medicine
3. Structure and function of the cardiovascular system
4. Molecular embryology of the cardiovascular system
5. Molecular mechanisms of cardiac electrical generation, conduction and regulation
6. Ion channel genomics and proteomics
7. Molecular structure and function of the myocardium
8. Molecular correlations of the myocardium with skeletal and smooth muscles
9. Genetic and molecular basis of metabolic and nutritional cardiovascular regulation
10. Genetic and molecular pathophysiology of heart failure
11. Molecular aspects of arterial, venous and lymphatic circulation
12. Molecular mechanisms and pathophysiology of pulmonary arterial and venous hypertension
13. Molecular perspectives of the cardiovascular inflammation
14. Molecular mechanisms of cardiovascular system response to hyperlipidemia and hyperglycemia
15. Molecular pathology of coronary (ischemic) artery disease (CAD)
16. Molecular basis of the adverse drug and toxin response of the cardiovascular system
17. Precision and personalise cardiovascular medicine including Molecular cardiovascular therapeutics
18. Novel cellular and molecular cardiovascular therapeutics
19. Genomic and Molecular basis of cardiovascular phenotype ontology
20. Preventive and public health applications of the genomic and molecular cardiovascular medicine (including social, ethical and legal aspects)
21. Glossary- selection and explanation of pertinent terms & phrases
Professor Dhavendra Kumar is a Visiting Professor, Genomic Policy Unit, Faculty of Life Sciences and Education, The University of South Wales and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. He is one of the Consultants for the All Wales Medical Genetics Service and the lead Clinician for Clinical Cardiovascular Genetics. After qualifying in Medicine from the King George’s Medical College, University of Lucknow, India, he completed postgraduate training in Pediatrics with an MD. Since 1980 he has pursued a career in Medical Genetics in the UK. In 1990 he became a Diplomate of the American Board of Medical Genetics. He is a Fellow of the American College of Medical Genetics (FACMG) and as well as Royal Colleges of Physicians (FRCP-London and FRCP-Ireland) and Pediatrics and Child Health (FRCPCH-UK).
In 2015, he was conferred with the higher degree of DSc by his Alma Mater, King George’s Medical University, Lucknow (UP, India) based on his life-time contributions and achievements to genetic and genomic applications in medicine and health.
Dr. Arthur A. M. Wilde is a clinical Cardiologist and translational researcher with a focus in electrophysiology, cardiogenetics and inherited arrhythmias. In Amsterdam University Medical Centers (location AMC), his lab is one of the first worldwide to start an outpatient cardiogenetic clinic. Over the years they have seen thousands of patients and families with inherited arrhythmia syndrome. This is the basis of his Academic Research
- Includes clinical applications of genomic and molecular new knowledge, along with advances in the practice of cardiovascular medicine and surgery
- Provides wide coverage of all major clinical and preventive aspects of clinical cardiology, including multi-disciplinary team care
- Focuses on targeted gene and molecular therapy in clinical cardiovascular medicine and surgery
Date de parution : 05-2024
Ouvrage de 360 p.
19x23.3 cm
