Space,Time and Memory in the Hippocampal Formation, 2014

The discovery of new cell types, such as grid and time cells, in the hippocampus has been accompanied by major anatomical and theoretical insights in the recent years. This book provides comprehensive, up-to-date information about the hippocampal formation and especially the neural basis of episodic memory, spatial location (the formation of the cognitive map) and temporal representation.

The first part of the book describes the information flow from pre-hippocampal areas into the hippocampus, the second part discusses the different types of hippocampal processing and finally, the third part depicts the influence that the hippocampal processing has on other brain structures that are perhaps more closely tied to explicit cognitive or behavioral output. This book is intended for  neuroscientists, especially for those who are involved in research on the hippocampus, as well as for behavioral scientists and neurologists.

Hippocampal Inputs. The posterior parietal cortex: interface between maps of external spaces and generation of action sequences.- Perirhinal and postrhinal functional inputs to the hippocampus.- Head-direction cells.- Grid cells and boundary cells .-Spatial and nonspatial representations in the Lateral Entorhinal Cortex.-  Modulatory influences on the hippocampus and entorhinal cortex.-Path integration mechanisms.

Hippocampal Processing. Remapping and population coding to discriminate contexts.- Splitter cells:  hippocampal place cells whose firing is modulated by where the animal is going, or where it has been.- Time and the hippocampus - The function of oscillations in the hippocampal formation.- Memory replay in the hippocampus.-Computational and theoretical contributions to understanding how the hippocampal circuit performs spatial tasks.- Adult neurogenesis in the dentate gyrus.- Hippocampal neurophysiology across species.

Hippocampal Readout. Neural coding of context and fear by hippocampus and amygdala.- Interactions between the hippocampus and the striatum: anatomy, neural signals, and function.- Interactions of prefrontal cortex and hippocampal  function: goals, rules, and episodes.

From Function to Structure. Anatomical epilogue.

Dr. Dori Derdikman is assistant professor at the Department of Physiology, Rappaport Faculty of Medicine, Technion, in Haifa, Israel. Between 2006 and 2011 he was postdoctoral research fellow With Professor May-Britt and Edvard Moser at the Kavli Institute for Systems Neurosciences at the Center for Biology and Memory, in Trondheim, Norway and later with Dr. Nachum Ulanovsky at the Department of Neurobiology at the Weizmann Institute of Science in Rehovot, Israel.

Dr. James J. Knierim is Associate Professor at the Zanvyl Krieger Mind/Brain Institute and the Solomon Snyder Department of Neuroscience at Johns Hopkins University in Baltimore, USA.  After completing his doctoral dissertation on primate vision at Caltech, he was a postdoctoral fellow in the laboratory of Bruce McNaughton at the University of Arizona from 1992-1998.  He was an Assistant Professor and Associate Professor in the Department of Neurobiology and Anatomy at the University of Texas Medical School at Houston from 1998-2009.

Provides current information about recent advances in the hippocampal research field

Describes in a structured way information flow from pre-hippocampal areas to processing and read out

Depicts the newest discoveries in this field like time cells, grid cells, boundary cells, sequences and non spatial inputs