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Sex Differences in Cardiovascular Physiology and Pathophysiology

Langue : Anglais

Coordonnateurs : LaMarca Babbette, Alexander Barbara T.

Couverture de l’ouvrage Sex Differences in Cardiovascular Physiology and Pathophysiology

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.

Sex Steroid Receptors 1. Androgens, women and cardiovascular disease 2. Estrogen receptor signaling and cardiovascular function 3. The Protective Role of Estrogen and Brain Estrogen Receptors in the Pathogenesis of Hypertension 4. Sex differences in cerebral ischemia

Sex differences in Hypertension 5. Sex differences in the central control of sodium appetite and blood pressure 6. Sex differences in the role of the ATt2 receptor and blood pressure 7. Regulation of Postmenopausal Hypertension

Preeclampsia and longterm consequences 8. Preeclampsia spectrum disorders including PE, E, HELLP, GH and CHTN 9. Preeclampsia: cardiovascular and renal risk during and post pregnancy 10. The Cerebral circulation during pregnancy and preeclampsia

Role of Sex and Atherosclerosis 11. Sex differences and the role of the renin angiotensin system in atherosclerosis and abdominal aortic aneurysms 12. Sex Differences in Coronary Artery Disease

Role of Sex difference in autoimmunity and inflammation 13. Role of Sex Differences in autoimmunity and inflammation 14. Estrogen autoimmunity and Lupus 15. Gender and sex differences in autoimmune type-I diabetes

Sex Differences in Cardiac Function and Remodeling 16. Sex differences in the developmental programming of cardiovascular structure and function 17. Sex specific mechanisms of myocardial hypertrophy and heart failure

Sex steroids and cardiovascular disease, men versus women 18. Benefits and Risks of Testosterone Therapy in Men with Testosterone Deficiency 19. Sex, age and neurovascular control

Researchers, postdoctoral fellows, clinicians (particularly cardiologists, vascular surgeons, etc.), clinical fellows, and graduate students.

Dr. Babbette LaMarca completed her Ph.D. in 2004 from Microbiology/Immunology, postdoctoral training in Physiology and joined the UMMC faculty in 2008. She is a professor in Pharmacology and Toxicology with a secondary appointment in Ob/Gyn, as Thesis Director of Maternal Fetal Medicine Fellowship Program. She serves as peer reviewer for the AHA/Immunology Section, Preeclampsia Foundation, NIH/NHLBI since 2014 and was Chair-AHA Clinical Endothelial Vascular Biology Clinical 2014-2017. Dr Lamarca has published over 100 peer review articles and presented 150 abstracts at national or international meetings. She is active in the American Physiological Society and was the At-Large Councilor for Membership 2012-2016 for the Water and Electrolyte Homeostasis Section and has served on Committee on Careers in Physiology and currently serves on the Awards Committee 2016-2019, she is currently the Basic Science Councilor for Perinatal research society. Dr. LaMarca serves on Editorial Boards for Hypertension, AJP-Regu and Clinical and Experimental Hypertension. She is a mentor for UMMC Base Pair program, member of Institutional Biosafety Committee, Graduate Faculty, Research Advisory Committee, the Women’s Health Research Center, at UMMC. Her previous awards include the Young Investigator from Inter-American Society of Hypertension, 2012 Young Scholars from American Society of Hypertension, a recipient of Excellence in Research from UMMC (Bronze 2010, Silver 2012 and Gold 2013) and the 2015 recipient of the Henry Pickering Bowditch lectureship from the APS. Dr LaMarca utilizes various animal models of preeclampsia to examine mechanisms of this disease. Dr. LaMarca combines basic science with clinical research to investigate how inflammation mediates renal and placental dysfunction leading to hypertension during preeclampsia.
Dr. Barbara T. Alexander, Ph.D., FAHA, FAPS, Professor of Physiology and Biophysics at the University of Mississippi Medical Center (UMMC) in Jackson M
  • Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system
  • Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases
  • Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

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Ouvrage de 392 p.

21.4x27.6 cm

Disponible chez l'éditeur (délai d'approvisionnement : 14 jours).

146,54 €

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Thèmes de Sex Differences in Cardiovascular Physiology and... :

Mots-clés :

Abdominal aortic aneurysms; Acute coronary syndrome; Androgen receptor; Androgens; Anemia; Angiotensin; Atherosclerosis; Autoimmune disease; Autoimmune diseases; Autoimmunity; Autonomic nervous system; B-cells; Blood pressure; Bone mineral density; Brain estrogen receptor subtypes; Cardiac embolism; Cardiac output; Cardiovascular disease; Cardiovascular risk factors; Cerebral autoregulation; Cerebral circulation; Cerebral ischemia; Cerebrovascular disease; Chronic hypertension; Chronic kidney disease; Circumventricular organs; CNS sympathetic neural network; Coronary artery disease; Depressive symptoms; Developmental Origins of Health and Disease; Developmental Programming; Eclampsia; Endothelial function; End-stage renal disease; Energy metabolism; Estradiol; Estrogen; Estrogen receptors; Estrogens; Female; Fetus; Fibrosis; Gender differences; Gestational hypertension; Heart; Heart failure; HELLP syndrome; Hormone replacement therapy; Hypertension; Hypogonadism; Hypothalamus; Inflammation; iNKT cells; Intracranial hemorrhage; Ischemic stroke; Islet-specific autoantibodies; Kidney; Lupus; Lupus pregnancy; Lymphocytes; Macrophages; Menopause; Menstrual cycle; Metabolic syndrome; Mineralocorticoids; Mitochondria; Mortality; Myocardial infarction; Neuroinflammation; NOD mice; Nonobstructive coronary disease; Obesity; Outcomes; Oxytocin; Plasticity; Polycystic ovary syndrome; Postmenopausal hypertension; Preeclampsia; Preeclampsia/eclampsia; Pregnancy; PRES; Protective actions of estrogen in the brain; Quality of life; Renin-angiotensin system; Renin-angiotensin-aldosterone system; Risk factors; Salt appetite; Sensitization of the hypertensive response; Sex chromosomes; Sex differences; Sex differences and hypertension; Sex hormones; Sexual dimorphism; Sexual function; Stress; Stroke; Systemic lupus erythematosus; T-cells; Testosterone deficiency; Testosterone therapy; Tregs; Type 1 diabetes; Vascular; Vascular dysfunction; Vasculature; Vasoconstriction; Women