Retinal Development

This advanced text, first published in 2006, takes a developmental approach to the presentation of our understanding of how vertebrates construct a retina. Written by experts in the field, each of the seventeen chapters covers a specific step in the process, focusing on the underlying molecular, cellular, and physiological mechanisms. There is also a special section on emerging technologies, including genomics, zebrafish genetics, and stem cell biology that are starting to yield important insights into retinal development. Primarily aimed at professionals, both biologists and clinicians working with the retina, this book provides a concise view of vertebrate retinal development. Since the retina is 'an approachable part of the brain', this book will also be attractive to all neuroscientists interested in development, as processes required to build this exquisitely organized system are ultimately relevant to all other parts of the central nervous system.

Foreword Alan Bird; Preface; 1. Introduction Rachel O. L. Wong; 2. Formation of the eye field Michael E. Zuber and William A. Harris; 3. Retinal neurogenesis David H. Rapaport; 4. Cell migration Leanne Godinho and Brian Link; 5. Cell determination Michalis Agathocleous and William A. Harris; 6. Neurotransmitters and neurotrophins Rachael A. Pearson; 7. Emergence of the fovea Anita Hendrickson and Jan M. Provis; 8. Optic nerve formation David W. Sretavan; 9. Glial cells in the developing retina Kathleen Zahs and Manuel Esguerra; 10. Retinal mosaics Stephen J. Eglen and Lucia Galli-Resta; 11. Programmed cell death Rafael Linden and Benjamin E Reese; 12. Dendritic growth Jeff S. Mumm and Christian Lohmann; 13. Synaptogenesis and early neural activity Evelyne Sernagor; 14. Emergence of light responses Evelyne Sernagor and Leo M. Chalupa; New Perspectives: 15. Regeneration (and stem cells) Jennie Close and Thomas A. Reh; 16. Genomics Seth Blackshaw; 17. Zebrafish models of retinal development and disease James M Fadool and John E. Dowling.