Reproductive and Developmental Toxicology (3rd Ed.)
Coordonnateur : Gupta Ramesh C
Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife
With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies.
Section I. General Section II. Toxicity Testing Models, Safety Evaluation, and Regulatory Aspect Section III. Nanoparticles and Radiation Section IV. Gases and Solvents Section V. Drugs of Abuse and Addiction, Smoking, and Alcohol Section VIII. Pesticides, Industrial, and Other Environmental Contaminants Section IX. Phytotoxicants and Mycotoxins Section X. Special Topics Section XI. Endocrine Disruption Section XII. Infertility and Teratogenicity Section XIII. Toxicologic Pathology Section XIV. Placental Toxicity Section XV. Domestic and Wildlife Species
- Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development
- Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis
- Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more
Date de parution : 08-2022
Ouvrage de 1556 p.
21.5x27.6 cm
Thèmes de Reproductive and Developmental Toxicology :
Mots-clés :
Agonist; aGPCR; Allosteric; Allosteric modulator; Allosteric modulators; Allostery; Animal physiology; Antagonist; Behavioral pharmacology; Benzamidine; Bias; Biosensors; BLT1; Cell signaling; Computational biology; Conformation; Crystal structure; Endocannabinoid system; FFA1/GPR40; FFA4/GPR120; Free fatty acid; G protein; G protein-coupled receptor; G protein-coupled receptor (GPCR); G protein-coupled receptors; GPCR; GPCRs; GPR84; Inverse agonist; Leukotriene B4 receptor; Ligand bias; Molecular docking; Molecular pharmacology; NAM; Nanobodies; PAM; PAR; Pepducins; Probe-dependence; Rational design; Receptor heteromer; Signal transduction; Signaling; Sodium ion; 3D cellular culture; A-bomb survivors; Absorption; Adolescents; Adverse outcome (AO); Adverse outcome pathway (AOP); Alcohol exposure; Alternative model; Alternative model organisms; Alternativeto animal testing; Amphetamine