Prions and Diseases, 2013 Volume 1, Physiology and Pathophysiology

Chapter 1    Transmissible Spongiform Encephalopathy: from the High Middle Ages to Daniel Carlton Gajdusek
Paul Brown

Chapter 2    The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein
Glenn L. Millhauser

Chapter 3    Role of Cellular Prion Protein in the Amyloid-ß Oligomer Pathophysiology of Alzheimer’s Disease
Adam C. Kaufman, Stephen M. Strittmatter

Chapter 4    Cellular Prion Protein and Cancers
Wei Xin, Man-sun Sy, Chaoyang Li

Chapter 5    Insoluble Cellular Prion Protein
Wen-Quan Zou

Chapter 6    Protein Misfolding Cyclic Amplification
Fabio Moda, Sandra Pritzkow, Claudio Soto

Chapter 7    Cofactor Involvement in Prion Propagation
Surachai Supattapone, Michael B. Miller

Chapter 8    Prion Protein Conversion and Lipids
Jiyan Ma

Chapter 9    New Perspectives on Prion Conversion: Introducing a Mechanism of Deformed Templating
Ilia V. Baskakov

Chapter 10   Infectious and Pathogenic Forms of Prion Protein
Emiliano Biasini, David A. Harris

Chapter 11   Cellular Mechanisms of Propagation and Clearance
Hermann M. Schatzl

Chapter 12    Molecular Mechanisms Encoding Quantitative and Qualitative Traits of Prion Strains
Jiri G. Safar

Chapter 13    Modeling the Cell Biology of Prions
Richard Rubenstein, Robert B. Petersen

Chapter 14    Prion Strain Interference   
Charles R. Schutt, Ronald A. Shikiya, Jason C. Bartz
 
Chapter 15   Introduction to Yeast and Fungal Prions
Reed B. Wickner

Chapter 16   Yeast Prions are Pathogenic, in-register Parallel Amyloids
Reed B. Wickner, Herman K. Edskes, David A. Bateman, Amy C. Kelly, Anton Gorkovskiy

Authored by a team of leading researchers and clinicians

Updated knowledge and concepts on pathogenic prion proteins and prion diseases

Present state-of the art findings and hypotheses beyond prions and prion diseases

Includes supplementary material: sn.pub/extras