Principles and Applications of Therapeutic Ultrasound in Healthcare

Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound, details the system construction, introduces current and emerging applications, and discusses developing therapeutic ultrasound technologies.

Divided into two parts, the book first introduces the fundamentals of biomedical acoustics, discusses ultrasound calibration methods, and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials, outcome photos and illustrating figures, and a critical commentary on the challenges in this field.

The author discusses topics that include:

• The derivation of wave equation



• The mathematical solution of the wave propagation



• The phenomena of reflection



• Refraction and transmission in the acoustic field from different acoustic sources



• The radiation pattern of the ultrasound transducer



• The acoustical properties of biological tissues



• Ultrasound-induced bioeffects



• Cavitation



• The design of the ultrasound transducer



• The characterization method of the produced acoustic field

An easy reference offering full coverage of popular ultrasound therapies, Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics, including wave equation, propagation, nonlinearity, and transducer design. It also discusses other potential applications, and is geared toward academia, industry, and researchers.

Introduction. Wave Equation. Sound Reflection, Refraction, and Transmission. Acoustic Field and Wave Radiation. Acoustical Properties of Biological Tissue. Nonlinear Acoustics. Cavitation. Transducer. Acoustic Field Calibration and Measurement. Ultrasonic Physiotherapy. Hyperthermia. Shock Wave Lithotripsy and Treatment. High-Intensity Focused Ultrasound. Ultrasound-Mediated Drug Delivery/Gene Transfection. Future of Therapeutic Ultrasound.

Yufeng Zhou is an assistant professor at the School of Mechanical & Aerospace Engineering at Nanyang Technological University, Singapore. He earned his BS and MS in electrical science and engineering from Nanjing University, China, in 1996 and 1999, respectively, and a PhD in mechanical engineering from Duke University, Durham, North Carolina, in 2003. Dr. Zhou’s research interests are focused on biomedical ultrasound, including ultrasound diagnosis (i.e., elastography) and therapy (i.e., shock wave lithotripsy to break calculus, high-intensity focused ultrasound for cancer ablation, ultrasound-mediated drug/gene delivery). He is a senior member of the Institute of Electrical and Electronics Engineers and an advisory editorial board member of the journal Ultrasound in Medicine and Biology.