Point-of-care Glucose Detection for Diabetic Monitoring and Management

This book unravels the role of Point-of-Care (POC) glucose monitoring as an essential part of diabetes management. It provides the reader with an in-depth knowledge and understanding of diabetes management, including:

• the need for POC glucose monitoring





• the glucose detection technologies (invasive, noninvasive and continuous) being used in the POC devices





• the analytical performance, characteristics, pros and cons of the POC devices developed to date





• the importance and role of glycated hemoglobin (HbA1c) monitoring for diabetes management





• the various POC devices and analyzers for the determination of HbA1c.

This is the first book to provide complete up-to-date information on POC glucose detection technologies and devices for diabetic monitoring and management. It will be an important reference for healthcare professionals, biomedical engineers, researchers, economists and policy makers. This book also serves as an asset and teaching aid for professionals and researchers in diabetic monitoring and management.

Preface. 1. Diabetes: A growing epidemic and the need for point-of-care testing. 2. Blood glucose monitoring. 3. Non-invasive glucose monitoring. 4. Continuous glucose monitoring. 5. Glycated hemoglobin (HbA1c) monitoring for diabetic management and therapy. 6. Diabetes management software and smart applications. 7. Performance requirements, analytical accuracy and clinical accuracy of self-monitoring of blood glucose: a clinical perspective. 8. A concluding remark. Index

Dr. Sandeep K. Vashist is the Chief Scientific Officer at Vallo Med Health Care GmbH, Germany and Adjunct Full Professor at Biomedical Engineering, Vellore Institute of Technology, India. He was the Bioanalytical Scientist at Bristol-Myers Squibb Ireland (2006−2009), Team Leader for point-of-care (POC) diabetic monitoring at National University of Singapore (2009−2012), Head of Immunodiagnostics at Hahn-Schickard, Freiburg, Germany (2012-2015). He was a Visiting Senior Scientist in POCT at Klinikum rechts der Isar der TUM, Germany and Royal Melbourne Institute of Technology, Australia. His research outputs include many successful technology transfers; several assays, IVD and POCT technologies; >100 high impact factor journal publications and ~100 conference publications, numerous patents, several book chapters, and many invited/keynote/plenary talks. He has constantly received highly prestigious fellowships and awards for scientific research excellence and innovation. He is the Editor for more than 12 highly reputed journals (such as Sci Rep, Biochem Biophys Rep, New Horiz Transl Med, Neurol Psychiat Br, Biotech Adv, Diagnostics, Sensors, Biosensors etc.). Besides, he is the expert/reviewer/advisor/consultant for many international funding agencies, industrial and healthcare authorities/settings in the fields of assays, IVD, POCT, mobile healthcare, and diabetic monitoring and management.

Prof John H.T. Luong is the Walton Fellow and Professor associated with the Department of Chemistry of University College Cork, Ireland. He was the Professor and Division Head of Biomedical Engineering of Nanyang Technological University, Singapore. He was also a distinguished Visiting Professor at University of Zhengzhou (China), a Visiting Professor at Nanocore, National University of Singapore. He also spent over 30 years at the National Research Council Canada as the Head of Biosensor Technology and Nanobiotechnology and an