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Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction

Langue : Anglais

Coordonnateurs : Henkel Ralf, Samanta Luna, Agarwal Ashok

Couverture de l’ouvrage Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction

Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included.

This is a must-have reference in the area of oxidative stress and male reproductive function.

1. Basic Aspects 2. Clinical Aspects 3. Current approaches 4. Future developments 5. Conclusions

Reproductive biologists, reproductive endocrinologists, academic clinicians interested in male reproduction, andrologists, and embryologists
Ralf Henkel, BEd, PhD, Habil., studied Biology and Chemistry at the University of Marburg, Germany, and obtained his PhD in 1990. Ralf continued his post-doctoral training and obtained his Habilitation at the University of Giessen, School of Medicine in 1998. From 1998 to 2004, he was an Assistant, Associate and Extraordinary Professor, at the Justus-Liebig University of Giessen, Germany, before he accepted a Full Professorship at the Department of Urology at the University of Jena, Germany. From 2005 to 2020, he was Professor and Head of Department at the Department of Medical Bioscience at the University of the Western Cape, Bellville, South Africa. He is also Honorary Professor at the Universidad Peruana Cayetano Heredia, Lima, Peru, and Editor-in-Chief of Andrologia. Ralf has published more than 140 original and review articles as well as 46 book chapters and supervised more than 70 Hons/MSc/MD/PhD postgraduate students’ theses. For his research, Ralf received 16 awards. Ralf has received 26 research grants for numerous research projects to investigate the impact of oxidative stress on sperm functions, DNA fragmentation and fertilization, as well as the effects of Herbal Medicine on male reproductive functions including prostate cancer and benign prostatic hyperplasia.
Luna Samanta received her Ph.D. in 1999 from Utkal University, India. She first served as Assistant Professor in Biotechnology at Orissa University of Agriculture and Technology, India and subsequently as Assistant Professor in Zoology and Biotechnology at Utkal University, India. Luna was appointed as an Associate Professor of Zoology at Ravenshaw University, India in 2010. In 2014 she was promoted as Professor and Head of Department of Zoology. Currently she is the Dean, School of Life Sciences at Ravenshaw University. Luna was a Commonwealth Academic Fellow at the Institute of Reproductive and Developmental Biology, Imperial College London during 2012. She was also the recipient of Governme
  • Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches
  • Deals with current approaches to oxidative stress using OMICS platform<
  • Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology

Date de parution :

Ouvrage de 324 p.

21.4x27.6 cm

Disponible chez l'éditeur (délai d'approvisionnement : 14 jours).

121,37 €

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Thème d’Oxidants, Antioxidants, and Impact of the Oxidative... :

Mots-clés :

Acrosome reaction; Aerobic respiration; Aging; Antioxidant therapy; Antioxidant; Antioxidants; Apoptosis; ART; Biomarkers; Capacitation; Carbonylation; Chemiluminescence; Colorimetry; Cut-off point; Defective sperm; Diabetes; DNA damage; DNA fragmentation; Enzymatic antioxidants; Epigenetic alterations; Epigenetics; Evolution; Formazan; Free radicals; Galvanostat; Genomics; Glutathionylation; Great Oxygenation Event; Hyperactivation; Hyperthyroidism; Hypothyroidism; Immature spermatozoa; Infertility; Keyword; Leukocytes; Leukocytospermia; Lipid peroxidation; Lipid; Luminol; Luminometer; Male fertility; Male genital tract infections; Male infertility; Male reproduction; Malnutrition; Metabolic syndrome; Metabolite; Metabolomics; Microarray technique; Micronutrient deficiencies; Millivolts; MiOXSYS; Mitochondria; Mitochondrial DNA damage; Mobility; Mutagenic risk; NADH; NADPH; Nitro blue tetrazolium; Nonenzymatic antioxidants; Nuclear DNA damage; Obesity; Omics; Oocyte recognition; Oxidant paradox; Oxidation-reduction potential; Oxidative stress; Phosphorylation; Pregnancy; Proteolysis; Proteomics; PUFAS; Reactive nitrogen species; Reactive oxygen species (ROS)Sperm; Reactive oxygen species; Reducing agents; Reductive stress; Reference values; Relative light units; RNA sequencing; ROS; Semen analysis; Semen parameters; Semen; Seminal leukocytes; Seminal plasma; S-Nitrosylation; Sperm DNA damage; Sperm maturation; Sperm quality; Sperm-oocyte fusion; Sperm; Spermatogenesis; Spermatozoa; Superoxide anion; Superoxide; Telomeres; Testicular metabolism; Testis; Thyroid hormone; Transcriptomics; Treatments; Trolox equivalents; Ubiquitination; Varicocele; Varicocelectomy