Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci Advances in Immunology Series

Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens

As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.

1. Regulation and Evolution of the RAG Recombinase
   Grace Teng and David G. Schatz
2. Chromatin Interactions in the Control of Immunoglobulin Heavy Chain Gene Assembly
   Gita Kumari and Ranjan Sen
3. Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci
   Anja Ebert, Louisa Hill and Meinrad Busslinger
4. Long Range Regulation of V(D)J Recombination
   Charlotte Proudhon, Bingtao Hao, Ramya Raviram, Julie Chaumeil and Jane A. Skok
5. Dynamic Control of Long-range Genomic Interactions at the Immunoglobulin ? Light Chain Locus
   Claudia Ribeiro de Almeida, Rudi W. Hendriks and Ralph Stadhouders
6. Regulation of Tcrb Gene Assembly by Genetic, Epigenetic, and Topological Mechanisms
   Kinjal Majumder, Craig H. Bassing and Eugene M. Oltz
7. Chromatin Dynamics and the Development of the TCRa and TCRd  Repertoires
   Zachary Carico and Michael S. Krangel
8. Long-range Control of V(D)J Recombination & Allelic Exclusion: Modeling Views
   Pernelle Outters, Sébastien Jaeger, Nancy Zaarour and Pierre Ferrier
   

• Focuses on the generation of an effective immune response to invading pathogens
• Contains contributions from leading authorities
• Informs and updates on all the latest developments in the field of immunology