Molecular Determinants of Radiation Response, 2011 Current Cancer Research Series

Molecular Basis of the DNA Damage Responses.- ATM signaling and DNA Damage.- H2AX in DNA Damage Response.- Dynamic Imaging of DNA Damage Foci.- DNA Damage Signaling Downstream of ATM.- Checkpoint Control and Radiation.- Chromatin Responses to DNA Damage.-DNA Damage Response and Senescence.- C. elegans and DNA Damage.- Modulation of Radiation Responses – Opportunities for Therapeutic Exploitation.- The Stem Cell and Radiation.- Role of the Cell Membrane in Signaling Radiation Injury.- Hypoxia and Modulation of Cellular Radiation Response.- Role of PARP and PARP Inhibition in Cellular Response to Radiation.- Anti-angiogenic Therapies and Radiation Responses.- Gene Therapy and Radiation.- Radiation-mediated Molecular Targeting.- EGFR Signaling and Radiation.- Heat and Heat Shock Proteins Modulation of Radiation Response.- Radiation-induced Immune Modulation.