Methodological Approaches for Sleep and Vigilance Research

Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep.

1. Definitions and Measurements of the States of Vigilance
2. Polysomnographic Procedures as an Approach for Studying the Sleep-Wake Cycle
3. Electrophysiology studies in the Sleep-Wake Cycle
4. Tracking Single- and Multi-Unit Activity through the Sleep-Wake Cycle
5. Brain deep stimulation for understanding the sleep-wake phenomena
6. EEG functional connectivity and EEG power spectra in sleep
7. Multi-site recordings: From single cell to circuit level dissection of Sleep-wake in mice
8. Optogenetics and Sleep Research
9. Behavioral States Monitored by Telemetry
10. Wearable and Non-Wearable Sleep-Tracking Devices
11. Clinical Trial: Imaging Techniques in Sleep Studies
12. Objective Questionnaires for Assessment Sleep Quality
13. Genome-Wide Association Studies of Sleep Phenotypes
14. Artificial Intelligence as a Clinical Psychoinformatic Approach for the Analysis of the Behavioral States
15. Big Data Providing Insights for Sleep Medicine

Dr. Murillo-Rodríguez is a Psychologist and PhD in Biomedical Sciences, having completed his post-doctoral training at Harvard Medical School. He has served as editor of multiple journals such as The International Journal of Neuropsychopharmacology and PLoS ONE, among many others. He is a member of several scientific societies, including the Society for Neuroscience. He has received academic awards such as the Young Investigator Award from the World Federation of Sleep Research and Sleep Research Societies Society, and is a member of the National System of Researchers (Level 2) of the National Council of Science and Technology (México). He is also the author of The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy (Elsevier, May 2017).