Mathematical Modelling of Haemodialysis, 1st ed. 2019 Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics
Auteurs : Pstras Leszek, Waniewski Jacek
Beginning with an introduction to kidney function, renal replacement therapies, and an overview of clinical problems associated with haemodialysis, this book explores the principles of the short-term baroreflex regulation of the cardiovascular system and the mechanisms of water and solute transport across the human body from a mathematical model perspective. It synthesizes theoretical physiological concepts and practical aspects of mathematical modelling needed for simulation and quantitative analysis of the haemodynamic response to dialysis therapy.
Including an up-to-date review of the literature concerning the modelled physiological mechanisms and processes, the book serves both as an overview of transport and regulatory mechanisms related to the cardiovascular system and body fluids and as a usefulreference for the study and development of mathematical models of dynamic physiological processes.Mathematical Modelling of Haemodialysis: Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics is intended for researchers and graduate students in biomedical engineering, physiology, or medicine interested in mathematical modelling of cardiovascular dynamics and fluid and solute transport across the human body, both under physiological conditions and during haemodialysis therapy.
Introduction to renal replacement therapies and mathematical modelling in physiology.- Mathematical modelling in physiology.- Model structure, equations and parameters.- Model analysis and validation.- Simulation results and model outcomes.- Conclusions, challenges and future research directions.
Leszek Pstras is an Assistant Professor at the Laboratory of Mathematical Modelling of Physiological Processes at the Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences. His research focuses on mathematical modelling of cardiovascular short-term regulatory mechanisms as well as fluid and solute transport kinetics during haemodialysis therapy.
Date de parution : 08-2020
Ouvrage de 156 p.
15.5x23.5 cm
Date de parution : 07-2019
Ouvrage de 156 p.
15.5x23.5 cm
Thèmes de Mathematical Modelling of Haemodialysis :
Mots-clés :
renal replacement therapy; haemodialysis; kidney dialysis; baroreflex regulation; intradialytic hypotension; intradialytic hypertension; mathematical models; end-stage renal disease; ESRD; short-term cardiovascular baroreflex regulation; transport mechanisms; regulatory mechanisms; model-based simulations; water and solute transport
