Limbic Motor Circuits and Neuropsychiatry Routledge Revivals Series

Published in 1993. Limbic Motor Circuits and Neuropsychiatry explores the neural circuitry employed by mammals to interpret environmental stimuli that provoke adaptive behavioral responses. Internationally recognized biomedical scientists have contributed chapters that describe and evaluate the anatomy, physiology, pharmacology, and pathophysiology of how motivationally relevant environmental or interoceptive stimuli are translated into adaptive or maladaptive behavioral responses. The book also examines how classic limbic nuclei communicate with classic motor systems and the implications in neuropsychiatric disorders. This reference presents exciting new information that will interest neuroscientists, psychiatrists, neuropsychopharmacologists, and behavioral pharmacologists.

Basal Forebrain Organization: An Anatomical Framework for Motor Aspects of Drive and Motivation (L. Heimer, G.F. Alheid, D.S. Zahm). The Nucleus Accumbens Core and Shell: Accumbal Compartments and Their Functional Attributes (A.Y. Deutch, A.J. Bourdelais, D.S. Zahm). Transmitter Regulation of Mesencephalic Dopamine Cells (V. Seutin, R.A. North, S.W. Johnson). Functional Characteristics of Nucleus Accumbens Neurons: Evidence Obtained From In Vivo Electrophysiological Recordings (S.J. Henriksen, J. Giacchino). Transmitter Actions and Interactions on Pallidal Neuronal Function (T.C. Napier). Mesolimbic Interactions with Mesopontine Modulation of Locomotion (R.D. Skinner, E. Garcia-Rill). From Motivation to Action: A Review of Dopaminergic Regulation of Limbic ® Nucleus Accumbens ® Ventral Pallidum ® Pedunculopontine Nucleus Circuitries Involved in Limbic-Motor Integration (G.J. Mogenson, S.M. Brudzynski, M. Wu, C.R. Yang, C.C.Y. Yim). The Circuitry Mediating the Translation of Motivational Stimuli into Adaptive Motor Responses (P.W. Kalivas, L. Churchill, M.A. Klitenick). The Mesocorticolimbic Circuit in Drug Dependence and Reward-A Role for the Extended Amygdala? (G.F. Koob, P. Robledo, A. Markou , S.B. Caine). Limbic Cortico-Striato-Pallido-Pontine Substrates of Sensorimotor Gating in Animal Models and Psychiatric Disorders (N.R. Swerdlow, D.L. Braff, S.B. Caine, M.A. Geyer). Cortical Regulation of the Mesolimbic Dopamine System: Implications for Schizophrenia (B.K. Lipska, D.R. Weinberger). Magnetic Resonance Imaging of the Basal Ganglia in Depression (G.S. Figiel, C.B. Nemeroff). Mesolimbic Motor Circuit in Parkinson's Disease and Other Movement Disorders (E.K. Richfield).

Professional

Dr. Peter Kalivas , Ph.D., is Director of the Alcohol and Drug Abuse Program and Professor of Pharmacology in the Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology at Washington State University., Dr. Kalivas received his B.S. degree from Western Washington University in 1974 with a major in biology. In 1980 he received a Ph.D. in pharmacology at the University of Washington School of Medicine., After two years as a postdoctoral fellow in the Biological Sciences Research Center at the University of North Carolina, he became an Assistant Professor of Pharmacology at Louisiana State University Medical Center in New Orleans. He moved to Washington State University in 1984 where he was made Director of the Alcohol and Drug Abuse Program in 1989 and promoted to Professor of Pharmacology in 1990., Dr. Kalivas is a member of the American College of Neuropsychopharmacology, American Society of Pharmacology and Experimental Therapeutics, International Society for Neurochemistry, Society for Neuroscience and the Union of Concerned Scientists. He is the recipient of grants from the National Institute of Mental Health and the National Institute of Drug Abuse. He has authored more than 100 papers and edited five books., Dr. Kalivas’ research interests concern the topic of this book. He is studying the neural mechanisms whereby motivationally relevant environmental stimuli are translated into adaptive motor responses and the role they may play in psychiatric disorders, including substance abuse., Dr. Charles D. Barnes , Ph.D., is Professor and Chairman of the Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology in the College of Veterinary Medicine at Washington State University., Dr. Barnes received his B.S. degree from Montana State University in 1958 with double majors in biology and physics. In 1961 he received an M.S. degree in physiology and biophysics from the University of Washington, and in 1962 he earned his Ph.D. in