In Vivo Neuropharmacology and Neurophysiology, Softcover reprint of the original 1st ed. 2017 Neuromethods Series, Vol. 121

This volume presents classical approaches to in vivo neuropharmacology and neurophysiology, such as c-fos, electrochemistry, microdialysis microstimulation, and push-up superfusion. It also explores exciting new methods for behavioral analysis, and techniques based on optogenetics and non-invasive magnetic resonance imaging. The chapters of this book cover topics such as principles of stereotaxy, pharmaco-based fMRI and neurophysiology in humans and non-human primates, electrical nerve stimulation and central microstimulation, involvement of neurotransmitters in mnemonic processes, the impact of cannabinoids on motor activity, as well as the involvement of nitric oxide in neurotoxicity produced by psychostimulant drugs. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

Cutting-edge and practical, In Vivo Neuropharmacology and Neurophysiology is a valuable resource for experienced and less experienced investigators of brain function and brain disorders.

Preface...
Series Preface...

Part I Stereotaxy

1. Principles of Stereotaxy in Small Animals
Ariane Hornick,  Athineos Philippu

Part II Brain Function  

2.  EEG Indices of Cortical Network Formation and their Relevance for Studying Variance in Subjective Experience and Behavior
Thomas Koenig, Miralena I. Tomescu, Tonia Rihs, and Martha Koukkou

3.  Pharmaco-Based fMRI and Neurophysiology in Non-Human Primates
Daniel Zaldivar, Nikos K. Logothetis, Alexander Rauch, and Jozien Goense

4.  Optogenetic Manipulations of Neuronal Network Oscillations: Combination of Optogenetics and Electrophysiological Recordings in Behaving Mice
Tatiana Korotkova and Alexey Ponomarenko

5. 3D-Video-Based Computerized Behavioral Analysis for In Vivo Neuropharmacology and Neurophysiology in Rodents
Jumpei Matsumoto, Hiroshi Nishimaru, Taketoshi Ono, and Hisao Nishijo

6.  Operant Self-Administration of Chocolate in Rats: An Addiction-Like Behavior
Paola Maccioni and Giancarlo Colombo

7.  Electrical Nerve Stimulation and Central Microstimulation
Nikolaos  C. Aggelopoulos<

8.  In Vivo Biosensor Based on Prussian Blue for Brain Chemistry Monitoring: Methodological Review and Biological Applications
Pedro Salazar, Miriam Martín, Robert D. O’Neill,   José Luis González-Mora

9. <Monitoring Extracellular Molecules in Neuroscience by In Vivo Electrochemistry: Methodological Considerations and Biological Applications
José Luis González-Mora, Pedro Salazar, Miriam Martín, Manuel Mas

10.  Push-Pull Superfusion: A Technique for Investigating Involvement of Neurotransmitters in Brain Function
Athineos Philippou and Michaela M. Kraus

11.  Involvement of Neurotransmitters in Mnemonic Processes, Response to Noxious Stimuli and Conditioned Fear: A Push-Pull Superfusion Study
Michaela M. Kraus and Athineos Philippou

12.  Neurophysiological Approaches for In Vivo Neuropharmacology
Stephen Sammut, Shreaya Chakroborty, Fernando E. Padovan-Neto, J. Amiel Rosenkranz, and Anthony R. West

13.  Involvement of Neurotransmitters in Behavior and Blood Pressure Control
Dimitrios Kouvelas, Georgios Papazisis, Chryssa Pourzitaki, and Antonios Goulas

14.  Functional Mapping of Somatostatin Receptors in Brain: In Vivo Microdialysis Studies
Andreas Kastellakis, James Radke, and Kyriaki Thermos

15.  The Impact of Cannabinoids on Motor Activity and Neurochemical Correlates 
Katerina Antoniou, Alexia Polissidis, Foteini Delis, and Nafsika Poulia

Part III Brain Disorders

16. Modeling Schizophrenia:  Focus on Developmental Models
Axel Becker

17. Immunohistochemical Analysis of Fos Protein Expression for Exploring Brain Regions Related to Central Nervous System Disorders and Drug Actions
Higor A. Iha, Naofumi Kunisawa, Kentaro Tokudome, Takahiro Mukai, Masato Kinboshi, Saki Shimizu, and Yukihiro Ohno

18.  Involvement of Nitric Oxide in Neurotoxicity Produced by Psychostimulant Drugs
Valentina Bashkatova

Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts

Includes supplementary material: sn.pub/extras