Immunotherapy of Melanoma, Softcover reprint of the original 1st ed. 2016

This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer.

Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epidemiology, susceptibility genes, and treatment recommendations from Society for Immunotherapy of Cancer, as well as immune based therapies such as aldesleukin, Intron-A, Sylatron, Yervoy, Opdivo, Keytruda, Imlygic, DC vaccines and adoptive cell therapy.

With 132 illustrations including synopsis tables for important information, over 1200 references (majority of which are openly accessible) and details of more than 150 ongoing clinical trials, this book is a valuable source of information for health care providers as well as cancer biologists interested in learning about melanoma and the significant advances made by immunotherapy. 

Contents

Preface

1. Melanoma

            1.1 Introduction, history and epidemiology

            1.2 Diagnosis, subtypes and staging

            1.3 Etiology

2. Tumor immunology

            2.1 Overview of immune system

            2.2 Dendritic cells

            2.3 T-cells

3. Immune based drugs approved for treatment of melanoma<

            3.1 IFN-α2b

            3.2 IL-2

            3.3 Ipilimumab

            3.5 Pembrolizumab

            3.6 Talimogene laherparepvec

4. Promising immunotherapeutic approaches in clinical trials

            4.1 Introduction

            4.3 Cytokines

            4.4 Cancer vaccines

            4.6 Adoptive cell therapy

5. Challenges of immunotherapy

Index

Carefully written chapters useful for both basic and advanced oncologists and/or immunologists

Detailed and at the same time not-too-boring presentation of information on melanoma and immunotherapy

Over 1200 references (majority of which are available online)

Information on more than 150 clinical trials

Presentation of important information in the form synopsis in every chapter

Includes supplementary material: sn.pub/extras