Human Reproductive Genetics Emerging Technologies and Clinical Applications
Coordonnateurs : Garcia-Velasco Juan A., Seli Emre
Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion.
Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction.
2. Identification of Genetic Causes of Gynecologic Disorders
3. Cytogenetics
4. Molecular biology approaches utilized in pre-implantation genetics: real time PCR, microarrays, next generation sequencing, karyomapping, and others
5. Epigenetics and Imprinting In ART
6. The Quest for Genetic Sequence Variants Conferring Risk of Endometriosis
7. Genetics of PCOS
8. Male Factor Infertility: Genetic and Epigenetic Aspects
9. Mitochondrial Genetics
10. Endometrial Receptivity and Genetics
11. Genetics of Reproductive Aging and POF
12. Prenatal Testing
13. Carrier Testing in Reproductive Medicine
14. PGT-A (PB, Day 3, Day 5…)
15. Future Technologies for Pre-Implantation Genetic Applications
16. Counseling: Psychology of Genetic Diagnoses
17. Bioethics in Human Reproduction
18. The Role of Genetic Counseling in the Infertile Patient
Dr. Seli is Professor of Obstetrics, Gynecology, and Reproductive Sciences at Yale School of Medicine and Chief Scientific Officer at IVIRMA Global. He received his medical degree from the University of Istanbul and completed his Residency in Obstetrics and Gynecology at Yale University. His postdoctoral training included a fellowship in Reproductive Endocrinology and Infertility as well as a research fellowship in molecular biology, both at Yale University. As a physician-scientist, his primary focus is to understand and treat infertility. His laboratory characterized the mechanisms regulating translational activation of gene expression in the oocyte. Dr. Seli and his colleagues also made seminal contributions to our understanding of oocyte and embryo competence in IVF and the potential role of non-invasive diagnostic technologies in this context
- Provides an essential reference for clinicians involved in reproductive medicine
- Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients
- Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more
Date de parution : 04-2020
Ouvrage de 340 p.
19x23.3 cm