Hereditary Diseases and Blood Transfusion, Softcover reprint of the original 1st ed. 1995 Proceedings of the Nineteenth International Symposium on Blood Transfusion, Groningen 1994, organized by the Red Cross Blood Bank Groningen-Drenthe Developments in Hematology and Immunology Series, Vol. 30

Proceedings of the Nineteenth Annual International Symposium on Blood Transfusion, Groningen 1994, organized by the Red Cross Blood Bank, Groningen--Drenthe

I. Blood Coagulation.- The Molecular Biology of Haemophilia.- Molecular Biology of the Various Types of Von Willebrand Disease.- Molecular Basis of Thrombophilia.- Inhibitory Sequences Within the Clotting Factor VIII cDNA Block Transcriptional Elongation and Complicate Efforts Toward Gene Therapy for Haemophilia A.- II. Haemoglobin and Red Cells.- Globin Gene Regulation.- Molecular Pathology of the Thalassaemia Syndromes.- The Current Status of Bone Marrow Transplantation and Gene Therapy in the Management of TheHaemoglobinopathies.- The Molecular Biology of Blood Groups: Relevance to the Study of Erythroid Maturation and the Clinical Management of Haemolytic Disease of the Newborn.- Genetic Abnormalities in Blood Group Serology.- III. White Cells and Malignancies.- The Role of The Blood Bank in Human Gene Therapy Trials.- Translocation in Cancer: Mechanism of Oncogenic Conversion and Implications for Therapy.- Role of Topoisomerase II A and B Isozymes in Determining Drug Resistance In Vitro and In Vivo.- Impact of Cell Culture Technology on Transfusion Medicine.- Gene Therapy for Primary Immune Deficiencies.- IV. Gene Technology, Ethics and the Future.- Ethics and Genetic Manipulation.- Is There a Role for Transfusion Medicine in the Genetic Correction of Genetic Disorders and Other Diseases?.- Vectors for Gene Therapy: Strategies for Making Gene Therapy Work.- From Blood Stain to Pathogenesis Study of Human Hereditary Diseases.- The Potential Impact of Gene Therapy in Blood Transfusion.