GABA and Sleep, 2010 Molecular, Functional and Clinical Aspects
Coordonnateurs : Monti Jaime M., Pandi-Perumal Seithikurippu Ratnas, Möhler Hanns
GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. The GABA system is, therefore, of prime clinical relevance for the therapy of insomnia.
The focus of this volume is on the neuropsychopharmacology and the clinical impact of the GABA system in regulating sleep and wakefulness. It presents molecular, neuropharmacological, systems-biological and clinical approaches to the understanding of the mechanism of action of GABA and GABAergic drugs. It also explores the role of GABA in the basic drives that affect sleep, and the influences that adapt sleep and wakefulness to external events.
Focuses on the neuropsychopharmacology of GABA and its role in sleep and wakefulness
Presents neurochemical, electrophysiological, and neuropharmacological approaches to understand GABAergic mechanisms
Offers an overview of current approaches and medications
Features contributing authors who are leading experts in the field of sleep and neuropharmacology
Includes supplementary material: sn.pub/extras
Date de parution : 09-2014
Ouvrage de 486 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 210,99 €
Ajouter au panierDate de parution : 09-2010
Ouvrage de 486 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 210,99 €
Ajouter au panier