Fiber Deficiency and Colonic Disorders, Softcover reprint of the original 1st ed. 1975

Epidemiologists, on the basis of studies carried out chiefly in Africa, have suggested that depletion of fiber in the modern Western diet affects health adversely. D. P. Burkitt, who has been in the forefront of this investigation, has included among the "diseases of civilization" hiatus hernia, ischemic heart disease, cholelithiasis, polyps of the colon, and cancer of the colon. All of these conditions appear to have the same geographic distribution. In these areas, the diets were characterized by increased amounts of fat and meat protein, and by an apparent deficit of fiber. It is noteworthy that while an increased intake of refined sugars also has been implicated in the Western diet, the consumption of sugar and other sweetners in the United States actually has remained fairly stable since about 1925 when the use of complex carbohydrates in the form of starchy foods began to decline. The mechanism whereby deficiency of fiber in the diet contributes to the development of colonic diverticula, presumably is by facilitating the development of segmentation of the colon and pockets of intracolonic high pressure zones associated with prolonged transit time of bowel content. Preliminary therapeutic observations, furthermore, have suggested that the addition of fiber in the form of bran to the diet may promote regularity of bowel function and perhaps lessen the likelihood that new diver­ ticula will be formed after the resection of involved colonic segments.

I. Dietary Fiber and Interaction With Bacteria and Bile.- Dietary Fiber.- The Interrelationship Between Bile Acids, Bacteria and Dietary Fiber.- Bile Salts and Fiber.- II. Fiber and Colonic Function.- Absorption From the Human Colon.- Electromyogram of the Cat Colon and Colonic Flow.- Fiber, Bulk and Colonic Activity.- III. Fiber Deficient Disorders of the Colon.- Fiber Deficiency and the Irritable Colon Syndrome.- Diverticular Disease (Pathology).- Fiber Deficiency and Diverticular Disease of the Colon.- Surgical Aspects of Diverticular Disease.- Fiber Deficiency and Colonic Tumors.- IV. General Discussion Chairmen: Joseph B. Kirsner and Richard W. Reilly.- V. Summary.- Participants.