Greenson - Diagnostic Pathology: GI (4^th Ed.)

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of gastrointestinal pathology to help pathologists differentiate between closely related digestive tract disorders, this volume incorporates the most up-to-date scientific and technical knowledge, providing a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the fourth edition of Diagnostic Pathology: Gastrointestinal is a visually stunning, one-stop resource for every practicing pathologist, fellow, resident, or student as an ideal day-to-day reference or as a reliable training resource, and is useful to even the most experienced pathologist for current details on the diagnosis and characterization of neoplastic and nonneoplastic diseases of the digestive tract.

• Covers all areas of gastrointestinal pathology-from esoteric topics like microsporidia to common issues like serrated colorectal polyps
• Includes important new material on recently discovered genetic alterations in GI cancers, targeted gene therapies, and the changed approach to GI endocrine neoplasms, as well as numerous new chapters on other timely issues, such as COVID-19’s effects on the GI system, drug-induced GI diseases, and more
• Contains significantly updated information throughout, including new content, images, and references that reflect the most current diagnoses, provide ease for daily case sign-out, and contain details related to the latest WHO Classification of Tumours: Digestive System Tumours
• Features more than 2,400 print and online-only images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, and radiology images to help practicing and in-training pathologists reach a confident diagnosis
• Employs consistently templated chapters, bulleted content, key facts, annotated images, and an extensive index for quick, expert reference at the point of care
• Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date

. 10-15 new chapters plus image, text, and Reference updates across the book's ~200 chapters are in place for the 4th ed. of DP: Gastrointestinal. New chapters are added, and existing contents are updated, to address the newest WHO Classification of Digestive System Tumors. The updated Classification includes a change to how appendiceal neoplasms are classified. Additional new content covers the changed overall approach to gastrointestinal endocrine neoplasms and how to differentiate Grade 3 endocrine tumors from high grade neuroendocrine carcinomas. New 4th ed chapters also include details on targeted gene therapies and important genes now identified which involve primary cancers of the GI tract.

SECTION 1: ESOPHAGUS

NONNEOPLASTIC

4 Tracheoesophageal Fistula and Esophageal Atresia
Alexandros D. Polydorides, MD, PhD
8 Esophageal Duplication Cyst
Alexandros D. Polydorides, MD, PhD
12 Inlet Patch
Alexandros D. Polydorides, MD, PhD
16 Esophageal Webs and Rings
Alexandros D. Polydorides, MD, PhD
18 Esophageal Diverticula
Alexandros D. Polydorides, MD, PhD
24 Esophageal Varices
Alexandros D. Polydorides, MD, PhD
26 Esophageal Tears and Perforations
Alexandros D. Polydorides, MD, PhD
28 Achalasia
Alexandros D. Polydorides, MD, PhD
32 Gastroesophageal Reflux Disease
Alexandros D. Polydorides, MD, PhD
38 Eosinophilic Esophagitis
Alexandros D. Polydorides, MD, PhD
42 Pill-Induced Esophagitis
Elizabeth A. Montgomery, MD
46 Corrosive Damage (Lye)
Elizabeth A. Montgomery, MD
48 Sloughing Esophagitis
Alexandros D. Polydorides, MD, PhD
52 Candidal Esophagitis
Joel K. Greenson, MD
54 HIV-Associated Esophageal Ulcers
Joel K. Greenson, MD
56 Barrett Esophagus
Elizabeth A. Montgomery, MD

NEOPLASTIC

68 Dysplasia in Barrett Esophagus
Elizabeth A. Montgomery, MD
78 Adenocarcinoma, Esophagus
Elizabeth A. Montgomery, MD
84 Squamous Papilloma
Elizabeth A. Montgomery, MD
86 Squamous Dysplasia
Elizabeth A. Montgomery, MD
92 Squamous Cell Carcinoma, Esophagus
Elizabeth A. Montgomery, MD
98 Fibrovascular Polyp
Elizabeth A. Montgomery, MD
102 Granular Cell Tumor
Elizabeth A. Montgomery, MD

SECTION 2: STOMACH

NONNEOPLASTIC

108 Pyloric Stenosis
Elizabeth A. Montgomery, MD and Scott R. Owens, MD
110 Gastric Antral Vascular Ectasia
Gregory Y. Lauwers, MD
112 Dieulafoy Lesion
Alexandros D. Polydorides, MD, PhD
116 Portal Hypertensive Gastropathy
Gregory Y. Lauwers, MD
118 Acute Hemorrhagic Gastritis
Gregory Y. Lauwers, MD
120 Chemical Gastropathy
Gregory Y. Lauwers, MD
124 Gastric Mucosal Calcinosis
Gregory Y. Lauwers, MD
126 Iron Gastropathy
Gregory Y. Lauwers, MD
128 Gastric Ulcers
Gregory Y. Lauwers, MD
130 Carditis
Elizabeth A. Montgomery, MD and Scott R. Owens, MD
132 Helicobacter pylori Gastritis
Gregory Y. Lauwers, MD
136 Helicobacter heilmannii Gastritis
Joel K. Greenson, MD
138 Multifocal Atrophic Gastritis
Gregory Y. Lauwers, MD
140 Autoimmune Gastritis
Gregory Y. Lauwers, MD
144 Lymphocytic Gastritis
Gregory Y. Lauwers, MD
148 Eosinophilic Gastroenteritis
Gregory Y. Lauwers, MD
150 Focally Enhanced Gastritis
Gregory Y. Lauwers, MD
152 Collagenous Gastritis
Gregory Y. Lauwers, MD
154 Granulomatous Gastritis
Gregory Y. Lauwers, MD
156 Phlegmonous Gastritis
Elizabeth A. Montgomery, MD and Scott R. Owens, MD
158 Herpes Zoster Infection
Joel K. Greenson, MD
160 Gastric Xanthoma
Gregory Y. Lauwers, MD
162 Hyperplastic Polyps, Stomach
Gregory Y. Lauwers, MD
166 Ménétrier Disease
Gregory Y. Lauwers, MD
168 Zollinger-Ellison Syndrome
Gregory Y. Lauwers, MD

NEOPLASTIC

170 Fundic Gland Polyp
Gregory Y. Lauwers, MD
172 Adenoma/Dysplasia, Stomach
Gregory Y. Lauwers, MD
178 Adenocarcinoma, Stomach
Gregory Y. Lauwers, MD
186 Adenocarcinoma, Special Variants
Gregory Y. Lauwers, MD
190 Molecular Classification of Gastric Cancer
Gregory Y. Lauwers, MD
194 Hereditary Diffuse Gastric Cancer
Joel K. Greenson, MD
196 Well-Differentiated Neuroendocrine Tumor
(Carcinoid), Stomach
Gregory Y. Lauwers, MD
202 MALT Lymphoma
Scott R. Owens, MD
210 Gastroblastoma
Elizabeth A. Montgomery, MD
214 Plexiform Fibromyxoma
Elizabeth A. Montgomery, MD

SECTION 3: SMALL INTESTINE

NONNEOPLASTIC

220 Small Intestine Duplication Cyst
Joel K. Greenson, MD
222 Meckel Diverticulum
Joel K. Greenson, MD
224 Gastric Heterotopia
Joel K. Greenson, MD
226 Ectopic Pancreas
Joel K. Greenson, MD
228 Microvillous Inclusion Disease
Joel K. Greenson, MD
230 Necrotizing Enterocolitis
Joel K. Greenson, MD
232 Primary Lymphangiectasia
Joel K. Greenson, MD
234 Lymphangioma
Alexandros D. Polydorides, MD, PhD
238 Peptic Duodenitis/Duodenal Ulcer
Joel K. Greenson, MD
240 Celiac Disease
Joel K. Greenson, MD
246 Tropical Sprue
Joel K. Greenson, MD
250 Bacterial Overgrowth/Stasis
Joel K. Greenson, MD
252 Olmesartan Enteropathy
Joel K. Greenson, MD
254 Autoimmune Enteropathy
Joel K. Greenson, MD
258 Pouchitis
Joel K. Greenson, MD
260 Whipple Disease
Joel K. Greenson, MD
264 Common Variable Immunodeficiency
Joel K. Greenson, MD
268 Giardia
Joel K. Greenson, MD
270 Cryptosporidia
Joel K. Greenson, MD
274 Cystoisospora (Isospora)
Joel K. Greenson, MD
276 Cyclospora
Joel K. Greenson, MD
278 Microsporidia
Joel K. Greenson, MD
280 Yersinia
Gregory Y. Lauwers, MD
284 Mycobacterium avium-intracellulare
Gregory Y. Lauwers, MD
286 Mycobacterium tuberculosis
Gregory Y. Lauwers, MD
288 Strongyloides
Joel K. Greenson, MD

NEOPLASTIC

292 Adenoma, Small Intestine
Joel K. Greenson, MD
294 Adenocarcinoma, Small Intestine
Joel K. Greenson, MD
296 Well-Differentiated Neuroendocrine Tumor
(Carcinoid), Small Intestine
Joel K. Greenson, MD
302 Gangliocytic Paraganglioma
Elizabeth A. Montgomery, MD
308 Enteropathy-Associated T-Cell Lymphoma
Scott R. Owens, MD
314 Follicular Lymphoma, Duodenal Type
Scott R. Owens, MD
316 GI Tract Clear Cell Sarcoma-Like Tumor
Elizabeth A. Montgomery, MD
320 Waldenström Protein
Scott R. Owens, MD

SECTION 4: APPENDIX

NONNEOPLASTIC

326 Acute Appendicitis
Elizabeth A. Montgomery, MD and Scott R. Owens, MD
330 Granulomatous Appendicitis
Joel K. Greenson, MD
332 Enterobius vermicularis Appendicitis
Elizabeth A. Montgomery, MD and Scott R. Owens, MD
334 Fibrous Obliteration
Scott R. Owens, MD

NEOPLASTIC

336 Serrated Polyps, Appendix
Scott R. Owens, MD
338 Appendiceal Mucinous Neoplasms
Scott R. Owens, MD
346 Well-Differentiated Neuroendocrine Tumor
(Carcinoid), Appendix
Scott R. Owens, MD
350 Goblet Cell Adenocarcinoma (Goblet Cell Carcinoid)
Scott R. Owens, MD

SECTION 5: COLON

NONNEOPLASTIC

358 Hirschsprung Disease
Alexandros D. Polydorides, MD, PhD
364 Colonic Duplications, Cysts, and Congenital
Diverticula
Alexandros D. Polydorides, MD, PhD
366 Motility Disorders
Scott R. Owens, MD
368 Diverticular Disease
Alexandros D. Polydorides, MD, PhD
374 Endometriosis
Joel K. Greenson, MD
378 Preparation Artifacts
Alexandros D. Polydorides, MD, PhD
380 Melanosis Coli
Alexandros D. Polydorides, MD, PhD
384 Ulcerative Colitis, Colon
Scott R. Owens, MD
392 Crohn Disease
Alexandros D. Polydorides, MD, PhD
404 Lymphocytic Colitis
Alexandros D. Polydorides, MD, PhD
410 Collagenous Colitis
Alexandros D. Polydorides, MD, PhD
418 Eosinophilic/Allergic Colitis
Alexandros D. Polydorides, MD, PhD
424 Diversion Colitis
Joel K. Greenson, MD
426 Diverticular Disease-Related Colitis
Joel K. Greenson, MD
430 Solitary Rectal Ulcer Syndrome/Mucosal Prolapse
Alexandros D. Polydorides, MD, PhD
436 Pneumatosis Coli
Joel K. Greenson, MD
440 Sexually Transmitted Proctitis
Elizabeth A. Montgomery, MD
444 Acute Infectious Colitis
Gregory Y. Lauwers, MD
446 Focal Active Colitis
Joel K. Greenson, MD
448 Campylobacter
Gregory Y. Lauwers, MD
450 Salmonella
Gregory Y. Lauwers, MD
454 Shigella
Gregory Y. Lauwers, MD
456 Clostridium difficile
Gregory Y. Lauwers, MD
462 Enterohemorrhagic Escherichia coli
Gregory Y. Lauwers, MD
464 Spirochetosis
Gregory Y. Lauwers, MD
466 Adenovirus
Gregory Y. Lauwers, MD
468 Malakoplakia
Gregory Y. Lauwers, MD
470 Histoplasma
Gregory Y. Lauwers, MD
472 Cryptococcus
Gregory Y. Lauwers, MD
474 Entamoeba histolytica
Gregory Y. Lauwers, MD
476 Schistosomiasis
Gregory Y. Lauwers, MD

NEOPLASTIC

478 Benign Fibroblastic Polyp/Perineurioma
Elizabeth A. Montgomery, MD
482 Ganglioneuroma
Elizabeth A. Montgomery, MD
488 Hyperplastic Polyps, Colon
Alexandros D. Polydorides, MD, PhD
494 Sessile Serrated Adenoma
Alexandros D. Polydorides, MD, PhD
500 Mixed Adenoma-Serrated Polyp
Alexandros D. Polydorides, MD, PhD
502 Adenoma, Colon
Alexandros D. Polydorides, MD, PhD
510 Adenoma With Pseudoinvasion
Alexandros D. Polydorides, MD, PhD
512 Adenoma With Invasive Carcinoma
Alexandros D. Polydorides, MD, PhD
516 Colorectal Adenocarcinoma
Joel K. Greenson, MD
526 Familial Cancer Syndromes in Colorectal Carcinoma
Joel K. Greenson, MD
528 Familial Adenomatous Polyposis
Alexandros D. Polydorides, MD, PhD
534 Lynch Syndrome (Hereditary Nonpolyposis
Colorectal Cancer Syndrome)
Joel K. Greenson, MD
536 Serrated Polyposis
Elizabeth A. Montgomery, MD
540 Hereditary Mixed Polyposis Syndrome
Joel K. Greenson, MD
542 Inflammatory Bowel Disease-Associated Neoplasia
Alexandros D. Polydorides, MD, PhD
554 Well-Differentiated Neuroendocrine Tumor
(Carcinoid), Colon
Scott R. Owens, MD
556 Mastocytosis
Elizabeth A. Montgomery, MD and Scott R. Owens, MD

SECTION 6: ANUS

NONNEOPLASTIC

562 Hemorrhoids
Alexandros D. Polydorides, MD, PhD
566 Tailgut Cyst
Alexandros D. Polydorides, MD, PhD

NEOPLASTIC

570 Anal Intraepithelial Neoplasia
Scott R. Owens, MD
576 Squamous Cell Carcinoma, Anus
Scott R. Owens, MD
580 Basal Cell Carcinoma
Scott R. Owens, MD
582 Paget Disease
Scott R. Owens, MD
588 Anal Duct Carcinoma
Scott R. Owens, MD

SECTION 7: MULTIPLE ORGANS

NONNEOPLASTIC

592 Amyloidosis
Joel K. Greenson, MD
596 Cytomegalovirus
Joel K. Greenson, MD
602 Herpes Simplex Virus
Joel K. Greenson, MD
606 Nonsteroidal Antiinflammatory Drug (NSAID) Damage
Alexandros D. Polydorides, MD, PhD
612 Ischemia
Joel K. Greenson, MD
616 Vasculitis
Alexandros D. Polydorides, MD, PhD
624 Behçet Syndrome
Joel K. Greenson, MD
626 Graft-vs.-Host Disease
Joel K. Greenson, MD
632 Mycophenolate Injury
Joel K. Greenson, MD
634 Radiation Effect
Joel K. Greenson, MD
636 Immune Modulator Therapy Effect
Joel K. Greenson, MD
638 Chemotherapy Effect
Joel K. Greenson, MD
640 Taxane Effect
Elizabeth A. Montgomery, MD
644 Colchicine Toxicity
Elizabeth A. Montgomery, MD
646 Kayexalate Injury
Elizabeth A. Montgomery, MD
648 Cowden/PTEN Hamartoma Tumor Syndrome
Gregory Y. Lauwers, MD
656 Hamartomatous Polyps, Cronkhite-Canada
Gregory Y. Lauwers, MD
658 Hamartomatous Polyps, Juvenile
Gregory Y. Lauwers, MD
664 Hamartomatous Polyps, Peutz-Jeghers
Gregory Y. Lauwers, MD

NEOPLASTIC

670 Leiomyoma
Elizabeth A. Montgomery, MD
674 Leiomyosarcoma
Elizabeth A. Montgomery, MD
678 Gastrointestinal Stromal Tumor
Elizabeth A. Montgomery, MD
688 Mesenteric Fibromatosis
Elizabeth A. Montgomery, MD
692 Inflammatory Fibroid Polyp
Elizabeth A. Montgomery, MD
698 Schwannoma
Elizabeth A. Montgomery, MD
700 Inflammatory Myofibroblastic Tumor
Elizabeth A. Montgomery, MD
708 Glomus Tumor
Elizabeth A. Montgomery, MD
712 Primary Melanoma
Scott R. Owens, MD
714 Metastatic Melanoma
Elizabeth A. Montgomery, MD
726 Large B-Cell Lymphomas
Scott R. Owens, MD
732 Mantle Cell Lymphoma
Scott R. Owens, MD
736 Lipomatous Tumors
Alexandros D. Polydorides, MD, PhD
740 Follicular Dendritic Cell Sarcoma
Elizabeth A. Montgomery, MD