Development of the Nervous System (4th Ed.)
Auteurs : Sanes Dan H., Reh Thomas A., Harris William A., Landgraf Matthias
Development of the Nervous System, Fourth Edition provides an informative and up-to-date account of our present understanding of the basic principles of neural development as exemplified by key experiments and observations from past and recent times. This book reflects the advances made over the last few years, demonstrating their promise for both therapy and molecular understanding of one of the most complex processes in animal development. This information is critical for neuroscientists, developmental biologists, educators, and students at various stages of their career, providing a clear presentation of the frontiers of this exciting and medically important area of developmental biology.
The book includes a basic introduction to the relevant aspects of neural development, covering all the major topics that form the basis of a comprehensive, advanced undergraduate and graduate curriculum, including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity.
2. Polarity and Segmentation
3. Genesis and Migration
4. Generation of Neural Diversity
5. Wiring up the Brain: Axon Navigation
6. Differentiation
7. Naturally-Occurring Neuron Death
8. Synapse Formation
9. Refinement of Synaptic Connections
10. Behavioral Development
Dr. Reh is Professor of Biological Structure and Director of the Neurobiology and Behavior Program at the University of Washington. He is currently a member of the Scientific Advisory Board of the Foundation Fighting Blindness, and of a start-up biotechnology company, Acucela. He has received several awards for his work, including the AHFMR and Sloan Scholar awards and has published over 100 journal articles, reviews and books. Funded by numerous N.I.H. and private foundation grants, his lab is focused on the development and repair of the retina, with an overall goal of understanding the cellular and molecular biology of regeneration in the eye.
Dr. Harris is co-chair of Cambridge Neuroscience and Director of Studies in Neuroscience. He is also Head of the Department of Physiology, Development, and Neuroscience, and is Professor of Anatomy. Elected a Fellow of the Royal Society of London in 2007, he was Professor of Biology at UCSD prior to accepting a position at Cambridge. His lab is working to elucidate the cellular and molecular events that are used to push or induce cells to transition from proliferating stem cells to differentiated neurons and glia, and how particular regions of the nervous system produce the right number of neurons and the right proportions of different neuron subtypes.
Matthias Landgraf studied Genetics at University College London and completed his PhD research on nervous system development at the University of Camb
- Provides broad coverage of concepts and experimental strategies
- Includes full color schematics and photographs of critical experiments
- Outlines the molecular and genetic basis for most developmental events
- Written at a level that is appropriate for advanced undergraduates and beyond
- Includes designs of critical experiments that are easy to understand
Date de parution : 08-2019
Ouvrage de 390 p.
21.5x27.6 cm
