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Current Treatment Options for Fuchs Endothelial Dystrophy, Softcover reprint of the original 1st ed. 2017

Langue : Anglais

Coordonnateurs : Cursiefen Claus, Jun Albert S.

Couverture de l’ouvrage Current Treatment Options for Fuchs Endothelial Dystrophy

This book provides state of the art information on modern minimally invasive lamellar transplant techniques for Fuchs endothelial dystrophy (FED), such as Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK). In addition to clear step-by-step descriptions of procedures, guidance is offered on donor tissue preparation, potential intra- and postoperative complications, and complication management. Future treatment options in the form of medical, cell-based approaches are also discussed. To complete the picture, relevant information is included on the pathophysiology, clinical features, and differential diagnosis of FED. This book will be of interest to all who wish to learn about the dramatic developments in corneal transplantation and medical treatment that are transforming the management of FED.

Epidemiology and genetic basis of Fuchs Endothelial Corneal Dystrophy.- MicroRNAs in FED: New therapeutic option?.- Clinical phenotypes of Fuchs Endothelial Corneal Dystrophy (FECD), disease progression, differential diagnosis, and medical therapy.- Optical and anatomic changes in Fuchs Endothelial Dystrophy corneas.- Evolution of posterior lamellar keratoplasty: PK-DLEK-DSEK/DSAEK-DMEK-DMET.- DMEK Graft Preparation: eye bank perspective and risk factors for preparation failure.- Donor-tissue splitting and tissue storage for DALK and DMEK surgery.- DSAEK and UT-DSAEK in FED: Step-by-step approach.- DSAEK (not only) in Asian eyes: What glide to use? Optimized insertion techniques.- Intra- and postoperative complications and their management in DMEK.- DMEK: step-by-step surgical approach.- Complications of Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) surgery.- Revision for failed penetrating keratoplasty in FED.- Long-term clear graft survival and chronic endothelial cell loss following posterior lamellar keratoplasty.- Immune reactions and dry eye after posterior lamellar keratoplasty.- Tissue engineering of a healthy corneal endothelium for FECD patients.

Claus Cursiefen, MD, PhD, is Chairman and Professor in the Department of Ophthalmology at the University of Cologne, Germany and Adjunct Associate Scientist with the Schepens Eye Research Institute/Harvard Medical School, Boston. After completing his MD thesis at the Department of Anatomy, University of Würzburg, Dr. Cursiefen undertook a residency in the Department of Ophthalmology, Erlangen and a postdoctoral fellowship at the Schepens Eye Research Institute in Boston, MA. His clinical focus encompasses modern lamellar corneal transplant techniques (DMEK, DALK, DSAEK), artificial cornea, ocular surface reconstruction, cataract and glaucoma surgery, curative and refractive laser surgery, and ophthalmo-oncology. Dr. Cursiefen’s research has concentrated especially on mechanisms of corneal hem- and lymphangiogenesis and their implications for corneal transplant immunology. He is the author of more than 250 publications in the field, including in PNAS, Journal of Experimental Medicine, Journal of Clinical Investigation, and Nature Medicine.

Albert S. Jun, MD, PhD, is a board-certified opththalmologist who works at The Johns Hopkins Hospital, Baltimore, MD, USA,  and is Associate Professor of Ophthalmology at The Johns Hopkins University School of Medicine. He is also Associate Professor of Ophthalmology and Vice Chair for Education at the Wilmer Eye Institute. After gaining his PhD from Emory University Graduate School of Arts and Sciences, focusing on Genetics and Molecular Biology, Dr. Jun completed an Ophthalmology Residency at The Johns Hopkins Medical Institutions (1998–2001), a Cornea and External Disease Fellowship at Moorfields Eye Hospital (London, UK) (2001–2), and a Corneal Gene Therapy Research Fellowship at Imperial College School of Medicine (London, UK) (2002). He became a Diplomate of the  American Board of Ophthalmology in 2003. In 2013 he received an Achievement Award from the American Academy of O

Provides step-by-step descriptions of minimally invasive lamellar transplant techniques such as DSAEK and DMEK

Offers guidance on the management of complications

Examines emerging medical, cell-based approaches to Fuchs endothelial dystrophy

Date de parution :

Ouvrage de 255 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

Prix indicatif 116,04 €

Ajouter au panier

Date de parution :

Ouvrage de 255 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

Prix indicatif 158,24 €

Ajouter au panier

Thème de Current Treatment Options for Fuchs Endothelial Dystrophy :