Cell and Gene Therapies, 1st ed. 2019 Advances and Controversies in Hematopoietic Transplantation and Cell Therapy Series

In this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ongoing research. Each chapter focuses on a particular topic, and the concise text is supported by numerous working tables, algorithms, and figures. Whenever appropriate, guidance is provided regarding the availability of potentially high-impact clinical trials. The rapid evolution of cell and gene therapies is giving rise to numerous controversies that need to be carefully addressed. In meeting this challenge, this book will appeal to all residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant patients. It will also offer a robust, engaging tool to aid vital activities in the daily work of every hematology and oncology trainee.

Miguel-Angel Perales, MD, is a Medical Oncologist and Deputy Chief of the Adult Bone Marrow Transplant Service at Memorial Sloan Kettering Cancer Center in New York, where he also serves as Director of the Adult Stem Cell Transplant Fellowship.  He is a Special Contributing Faculty Member at the Gerstner Sloan Kettering Graduate School at MSK and an Associate Professor of Medicine at Weill Cornell Medical College.  He received his medical degree from the Universite Libre de Bruxelles and performed post-doctoral research and clinical training at Tufts Medical Center in Boston and Memorial Sloan Kettering Cancer Center in New York.  He serves on the Board of Directors of the National Marrow Donor Program (NMDP).  He is a member of a number of scientific associations and a member of the Alliance for Clinical Trials in Oncology (former CALGB) Transplant Committee, the American Society for Blood and Marrow Transplantation (ASBMT) Educational Committee (co-Chair) and Committee on Practice Guidelines, and the National Marrow Donor Program (NMDP) System Capacity Initiative Working Group and Curriculum Sub-Group.  He is a Co-Chair of the Center for International Blood and Marrow Transplant Research (CIBMTR) Graft Sources and Manipulation Working Committee and serves on a number of ad-hoc taskforces for the CIBMTR and Blood and Marrow Transplantation Clinical Trials Network (BMT CTN).  His research interests include translational research in stem cell transplantation for hematologic malignancies, immune reconstitution, tumor immunology, and the development of cytokine and cellular therapies for cancer.  Dr. Perales serves as a reviewer for several study sections and journals, and has authored over 100 peer-reviewed manuscripts, editorials, reviews and book chapters.

Syed A. Abutalib, MD Assistant Director, Stem Cell Transplant and Cell Therapy Program Cancer Treatment Centers of America.
Syed Abutalib, M.D., is Ass

Addresses key clinically relevant issues across the full spectrum of cell and gene therapies

Draws attention to the availability and implications of high-impact clinical trials

Assists trainee and practicing hematologists and transplant physicians in the delivery of optimal care