Care of the Jaundiced neonatal

Care of the Jaundiced Neonate focuses exclusively on the scientific underpinnings of jaundice, as well as the care of the jaundiced neonate. Edited by three of the field's most respected neonatal care experts, the book uniquely explains how the imbalance between bilirubin production and elimination leads to jaundice and that hazardous levels of unconjugated bilirubin can cause kernicterus, or brain damage. In addition, you'll find the most current and clinically relevant perspectives on the physiology, genetics, and treatment of neonatal jaundice and related hemolytic conditions. Covers all aspects of neonatal jaundice, from the biochemistry of bilirubin production to kernicterus. Begins with an in-depth examination of the complex gene-environment interactions of bilirubin-induced neurotoxicity and its role in neonatal jaundice. Surveys bilirubin production and measurement, its various fractions, and the metabolism and transport of bilirubin. Selected chapters highlight the physiology and epidemiology of neonatal unconjugated hyperbilirubinemia, bilirubin toxicity, prevention, screening, and postnatal management, phototherapy and other treatments and prevention-related public policy. Concluding chapter provides an overview of the key issues surrounding the incidence of neonatal jaundice in low-middle income countries. Includes informative review of risk assessment and treatment with phototherapy and other modalities provide key approaches to the effective clinical management of neonatal hyperbilirubinemia .

Chapter 1. Genetics of Neonatal Jaundice. Chapter 2. Bilirubin Production and Its Measurement. Chapter 3. Bilirubin and its Various Fractions. Chapter 4. Bilirubin Metabolism and Transport. Chapter 5. Physiology of Neonatal Unconjugated Hyperbilirubinemia. Chapter 6. The Epidemiology of Neonatal Hyperbilirubinemia. Chapter 7. Bilirubin Toxicity. Chapter 8. Hemolytic Disorders and Their Management. Chapter 9. Prevention, Screening and Postnatal Management of Neonatal Hyperbilirubinemia. Chapter 10. Phototherapy and Other Treatments. Chapter 11. Kernicterus. Chapter 12. Public Policy to Prevent Severe Neonatal Hyperbilirubinemia. Chapter 13. Neonatal Jaundice in Low-Middle-Income Countries.