Cardiac Regeneration using Stem Cells

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.

Induced Pluripotent Stem Cells. Human iPS cell generation methods for clinical usage. Reprogramming and Regenerative medicine: Unique approach via protein-derived iPS. Lessons from Heart Development to Regeneration. Directed and Systematic Differentiation of Cardiovascular Cells from Mouse and Human Pluripotent Stem Cells. Wnt Signaling in Cardiogenesis. The control of proliferation of pluripotent stem cell-derived cardiomyocyte. How to purify cardiomyocytes for research and therapeutic purposes. Ion channel expression and function of iPSC-derived cardiomyocytes. Pharmacology and Future Application of iPS Cell-derived Cardiomyocytes. Cardiac Regeneration Using Isl1-positive Cardiac Progenitor Cells. Cell Sheet Engineering for Heart Tissue Repair. Construction of functional cardiovascular tissues using magnetic nanoparticles. Jong-Kook Lee, Akira Ito, and Hiroyuki Honda. Cardiac cell therapy for ischemic heart disease. Induced Cardiomyocytes: Direct Reprogramming for Cardiac Regeneration. Modeling Arrhythmogenic Heart Disease with Patient-Specific Induced Pluripotent Stem Cells. In Vitro Generation of Efficacious Platelets from iPS Cells. Neuron Regeneration Using iPS Cells.

Fukuda, Keiichi; Yuasa, Shinsuke