Cardiac Biomarkers, 1st ed. 2016 Case Studies and Clinical Correlations

This book covers ACS and Heart Failure, the chapters represent the most current, up to date and knowledgeable content on the topic available. It is written by the worlds most respected leaders in biomarkers, with a majority emphasis on what clinicians need to know.

The patient with chest pain: The troponin story.- Troponin Basics for the clinician.- Pathophysiology of trop I and T in myocardial ischemia/infarction.- International Definition of MI- rationale and practice.- Evaluation of patients presenting with chest pain- where do troponins fit in.- Using contemporary troponin in patients with AMI.- Using troponins to guide therapy in ACS.- Use of cTn in patients with heart failure.- Elevated cTn in other acute situations.- Use of cTn for detection of more chronic disease states.- High sensitivity assays- what are they and why do we need them.- Use of troponin for the evaluation of patients potentially at risk for cardiovascular disease.- Gaps in our biomarker armamentarium – what novel biomarkers might be synergistic in patients with acute disease.- The patient with shortness of breath: the natriuretic peptide story.- Evaluation of patients presenting with sob- where do nps fit in.- Pathophysiology of bnp, and ntpro bnp.- A clinicians guide to lab assays for nps.- Using NPS in the ED- diagnosis.- Using NPs in the ED- algorithms and risk stratification.- Using NPs in the hospital.- NPs at the time of discharge.- Finger stick NP levels at home.- Guiding therapy of heart failure with NPs.- Caveats to NP measurement.- Other biomarkers for heart failure.- Biomarkers of cardiorenal disease,- Biomarkers of cardiac risk.​

Alan S. Maisel is a Professor of Medicine at the University of California, San Diego (UCSD). He is the Director of the Coronary Care Unit and Heart Failure Program at the VA San Diego Healthcare System in La Jolla, California. Dr. Maisel is active on the faculty at UCSD where he has won numerous teaching awards. Dr Maisel is considered one of the world’s experts on cardiac biomarkers and has over 300 scientific publications. He has authored several ground-breaking publications that have paved the way for development of diagnostic tools for patients with congestive heart failure. In particular, he was the leading investigator on studies that brought the use of BNP into clinical practice. Dr Maisel is also a writer of medical fiction. His first novel, Bedside Manners was optioned to Warner Brothers. His second novel, Brain Chicane, is about a young and idealistic physician working at the premier multiple-organ transplant hospital in Chicago where he investigates overdose cases that are not totally kosher.