Cancer and Chemoprevention: An Overview, Softcover reprint of the original 1st ed. 2017

This book focuses on the most recent, relevant, comprehensive and significant advances in cancer and chemo prevention. It broadly discusses cancer, its hallmarks and classification, molecular mechanisms of outbreak, contributing factors, role of oxidative stress, inflammatory mediators and evading apoptosis, which leads to the progression of disease.

Though modern medicine has left us with no option to treat this deadly disease due to drawbacks associated with conventional treatment ? like its non-targeted nature, drug resistance, varied organ toxicities and unaffordability ? chemoprevention offers a viable therapeutic window.

Introduction.- Hallmarks of Cancer.- Classification of Cancer.- Factors Influencing Cancer Development.- Carcinogenesis.- Molecular Mechanism of Carcinogenesis.- Oxidative Stress Induced Carcinogenesis.- Major Mediators Linking Inflammation and Cancer.-  Apoptosis.- Chemoprevention.- Classification of Chemopreventive Agents.- Preclinical Development of Chemo Preventive Agents for Chemoprevention.- Modulation of Wnt/β-Catenin Signaling by Chemo Prevention.- Modulation of Akt/mTOR Pathway Signaling by Chemo Prevention.- Novel Chemopreventive Agents.- Chemoprevention by Resveratrol.- Chemoprevention by Genistein.- Chemoprevention by Apigenin.- Chemoprevention by Curcumin.- Chemoprevention by Fisetin.- Chemoprevention by Epigallocatechin-3-gallate (EGCG).- Chemoprevention by Graviola.- Cancer Chemoprevention: Hurdles and Future Prospects and Considerations.- Clinical Trials of Chemoprevention.- Future of Chemoprevention.

Dr. Summya Rashid did her PhD from Department of Medical Elementology and Toxicology At Jamia Hamdard University, New Delhi, India and currently she is working as a research associate at the same place. Dr. Rashid has primarily worked on renal cell carcinoma and its various aspects. She possesses more than 5 years of research experience in the field of cancer biology and has contributed in 23 publications with h-index of 7. Dr. Rashid has attended various national and international conferences and workshops. In 2015, she was invited as honorary speaker at the International Conference on Antimicrobial Agents and Chemotherapy" at Valencia, Spain.