Biotechnology of Human Reproduction

Since the birth of the first successful IVF baby over twenty years ago, the field of assisted reproduction has grown exponentially. Preimplantation genetic diagnosis, gamete and embryo freezing, and embryo cloning are only a few examples of reproductive biotechnologies that have stimulated a worldwide debate.This book presents an up-to-date basis for this debate. It supplies a complete overview of how new biotechnologies benefit human reproductive medicine, from the viewpoints of both basic research and clinical application. It explores the most relevant issues in the field, including reproductive genetics, biology, pharmacology, endocrinology, surgery, and assisted reproduction technology. In each chapter, scientists and clinicians give insight into a particular aspect of human reproduction. The science and technology in this field has expanded beyond all expectations, and will only continue to grow. The wealth of information available and the continuing growth in this field creates a continuing need for up-to-date knowledge. This volume provides an expert and comprehensive overview of the field as it is understood and practiced today, and in the future.

Physiology of human reproductionNew Insights into Gametogenesis, Sperm migration, Fertilization and Implantation in Humans, A. Revelli, F. Poso, and I. Tur-Kaspa Ovarian Aging, Decline in Fertility Potential and Diminishing 'Ovarian Reserve', J. Holte Pharmacology of assisted reproductionSynthesis and Pharmacology of Recombinant Follicle Stimulating Hormone, H.J. Out GnRH: Synthesis, Pharmacology and Clinical Applications in Human Reproduction, D. Leivin, A. Weissman, and Z. Shoham The Role of Luteinizing Hormone in Ovulation Induction for Assisted Reproductive Technologies, G.N. Allahbadia and A. Phadnis Ovulation Induction Strategies in Women with Polycystic ovary Syndrome, G. Gennarelli, M. Massobrio, and J. Holte Human seminologyHuman Seminology: Semen Examination and in vitro Evaluation of Human Seminal Cells, A. Makler Assessment Techniques and Clinical Significance of Antisperm Antibodies (ASA), A. Lenzi, F. Lombardo, L. Gandini, and F. Dondero Fine Needle Aspiration Cytology of the Testis, C. Foresta, A. Bettella, M. Rossato, and D. Spolaore Sperm Testing by Hyaluronic Acid Binding: Andrologic Laboratory Assessment and Sperm Selection for ICSI, G. Huszar, A. Jakab, C. Celik-Ozenci, D. Sakkas, T. Kovacs, and L. Vigue Technologies for human in vitro fertilizationIVF in Humans: Technologies for Oocyte Retrieval, in vitro Insemination and Embryo Transfer, V. Karande and N. Gleicher In vitro Processing of Human Sperm for Assisted Reproduction, M. Rossato, C. Galeazzi, and C. Foresta Culture Media for the Human Embryo, D.K. Gardner and M. Lane Quality Assessment of Human Embryos: State of the Art and Future Perspectives, L.C. Krey Cryobiology of human reproductionTechnology for the Cryopreservation of Human Embryos and Gametes, E. Porcu, P.M. Ciotti, R. Fabbri, G. Damiano, A. Scarano , and S. Venturoli Cryopreservation of Testicular Tissue, O. Hovatta Cryopreservation of Ovarian Tissue, R. Fabbri, G. Bracone, C. Iannascoli and S. Venturoli In vitro maturation of human gametesIn vitro Maturation of Human Spermatozoa: An Update, J. Tesarik, C. Mendoza, and E. Greco In vitro Maturation of Human Follicles and Oocytes, G.M. Hartshorne Genetics of human reproductionGenetic Factors of Female Infertility, V,N. Zaporozhan and R.V. Sobolev Molecular Biology of the Human Y Chromosome, M. Kent-First Preimplantation Genetics in Human Embryology, L. Gianaroli, M.C. Magli, Al. Di Gregorio, and A.P. Ferraretti Micromanipulation techniques in human ivfMicromanipulation Techniques in Human Infertility: PZD, SUZI, ICSI, MESA, PESA, FNA, and TESE, F. Ubaldi and L. Rienzi Techniques for Embryo Manipulation in Human Reproduction: Assisted Hatching, Fragment Removal, Cytoplasmic Transfer, Nuclear Transfer, F. Moffa, J. Zhang, and A. Revelli New technologies in human infertilityModern Transcervical Techniques for the Diagnosis and Treatment of Tubal Obstruction, I. Tur-Kaspa The ART of Imaging: Three-Dimensional Ultrasound in A.R.T., I. Tur-Kaspa, S. Segal, and E. Zohav Endoscopic Technologies in Human Infertility, G.B. La Sala, M.T. Villani, and S. Gambino Laser Techniques in Assisted Reproductive Technologies, Y. Tadir Transgenic Models for the Study of Human Reproduction, K.H. Burns and M.M. Matzuk Stem cells biotechnology in human reproductionHuman Embryonic Stem Cells and Embryo Cloning, M. Amit, E. Suss-Toby, D. Manor, and J. Itskovitz-Eldor Transplantation of Male Germ Line Stem Cells: A Technique for Man? S. Schlatt