Biomarkers of Kidney Disease (2nd Ed.)
Coordonnateur : Edelstein Charles L.
Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book.
This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.
1. Characteristics of an Ideal Biomarker of Kidney Diseases 2. Statistical Considerations in Analysis and Interpretation of Biomarker Studies 3. The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools 4. The Role of Proteomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools 5. Cystatin C as a multifaceted biomarker in kidney disease and its role in defining “Shrunken Pore Syndrome 6. Biomarkers in acute kidney injury 7. Biomarkers of extra-renal complications of AKI 8. Biomarkers in kidney transplantation 9. Biomarkers of Renal Cancer 10. Proteomics and Advancements in Urinary Biomarkers of Diabetics Kidney Disease 11. Biomarkers of Cardiovascular Risk in Chronic Kidney Disease 12. Diagnostic and Prognostic Biomarkers in Autosomal Dominant Polycystic Kidney Disease 13. Biomarkers in Glomerular Disease 14. Biomarkers in Preeclampsia
Fellowships: University of Colorado (University Hospital) Program, Nephrology (1997)
- Explores both the practical and conceptual steps performed in the discovery of biomarkers in kidney disease
- Presents a comprehensive account of newer biomarker discover strategies, such as metabolomics and proteomics, all illustrated by clear examples
- Offers clear translational presentations by the top basic and clinical researchers in each specific renal disease, including AKI, transplantation, cancer, CKD, PKD, diabetic nephropathy, preeclampsia, and glomerular disease
Date de parution : 11-2016
Ouvrage de 632 p.
15x22.8 cm
Mots-clés :
biomarkers; acute kidney injury; chronic kidney disease; neutrophil gelatinase-associated lipocalin; interleukin-18; kidney injury molecule-1; cystatin C; ROC curves; true positive rate; false positive rate; accuracy; incremental value; molecular markers; combinatorial biomarkers; urine; NMR spectroscopy; GC-MS; LC-MS; biomarker qualification; biomarker development; regulatory requirements; drug toxicity; individualized medicine; 2D-gels; mass spectrometry; diagnostics; biomarker; Shrunken Pore Syndrome; GFR-estimating equations; creatinine; renal reserve; internal and external validation; acute kidney disease; IL-18; KIM-1; L-FABP; NGAL; TIMP2; IGFBP7; urinary glycosaminoglycans; brush-border enzymes; proinflammatory cytokines; serum cytokines; organ dysfunction; animal models; tissue markers; plasma markers; genetic markers; chemokines; renal cancer; prognosis; predicting response; diabetes; diabetes mellitus; kidney failure; protein identification; proteomics; nephropathy; GFR; albuminuria; proteinuria; ADPKD; genes; total kidney volume; renal blood flow; serum biomarker; urine biomarker; biological markers; biomarker discovery; focal segmental glomerulosclerosis; membranous nephropathy; minimal change disease; lupus nephritis; IgA nephropathy; prognostic; diagnostic; preeclampsia; angiogenic proteins; hypertension
