Biomarkers in Oncology, 2013 Prediction and Prognosis
Coordonnateur : Lenz Heinz-Josef
This integrated book covers the entire spectrum of cancer biomarkers in development and clinical use. Predictive and prognostic markers are explored in the context of colon cancer, breast cancer, lung cancer, prostate cancer, and GIST. International experts provide insight into toxicity markers and surrogate markers. Attention is also given to biomarker assay development, validation, and strategies.
A powerful tool for determining decisions on therapy, selecting drug regimens, monitoring the efficacy of treatment, and performing individualized surveillance, biomarkers represent the forefront of cancer research and treatment. As these technologies become increasingly available for clinical use, this book will be an essential resource for oncologists and translational researchers.
Ch. 1: Predictive Markers in Colon Cancer
Armin Gerger, Melissa J. LaBonte, and Heinz-Josef Lenz
Ch. 2: Prognostic Markers in Breast Cancer
Agustin A. Garcia, and Nazish Ahmad
Ch. 3: Predictive Markers in Lung Cancer
Stephen V. Liu, and Barbara J. Gitlitz
Ch. 4: Prostate Cancer: Predictive Markers in Clinical Development
Courtney K. Phillips, and Daniel P. Petrylak
Ch. 5: Biomarkers in GIST
Howard J. Lim, and Charles D. Blanke
Ch. 6: Cytogenetic and Molecular Aberrations as Predictive Biomarkers in Acute Myeloid Leukemia
Steffen Heeg, and Cornelius F. Waller
Ch. 7: Prognostic Markers in Colon Cancer
Janine M. Davies, and Howard L. McLeod
Ch. 8: Markers in Lung Cancer
Edwin Y. Lin, Ravin Rupani, and Barbara J. Gitlitz
Ch. 9: Molecular Markers of Prostate Cancer Outcome
David Ian Quinn, and Gregory P. Swanson
Ch. 10: Prediction of Chemotherapy Toxicities
Pierre Laurent-Puig, Thierry Lecomte, Marie-Anne Loriot, Valerie Boige, and Helene Blons
Ch. 11: Surrogate Markers—The Role of Positron Emission Tomography Scanning
Derek G. Power, and David H. Ilson
Ch. 12: Circulating Tumor Cells as Biomarkers
Amir Goldkorn, Tong Xu, and Stephen V. Liu
Ch. 13: Focus on Personalized Molecular Based Medicine
Lex HT Van der Ploeg, Bud Mishra, Casimir P. Eitner, Jon Burrows, Thomas Wray Tombler, Jr., Vladimir Poponin, Dan J. Knauer, Ilia Ichetovkin, Richard M. Pinnola, Gregory A. Endress, and Patrick Soon-Shiong
Ch. 14: Clinical Validation of Biomarkers
Sumithra J. Mandrekar, and Daniel Sargent
Ch. 15: Regulatory Issues
Maxwell T. Vergo, and Al B. Benson III
Ch. 16: Biomarkers for Safety Assessment and Clinical Pharmacology
Stan Louie, and Jared Russell
Ch. 17: Biomarker Discovery Strategies: DNA, RNA and Protein
Eduardo Vilar, and Josep Tabernero
Ch. 18: Biomarkers For Go/No Go Decisions
Ben Markman, and Josep Tabernero
Heinz-Josef Lenz, MD, FACP,
Division of Medical Oncology,
Norris Comprehensive Cancer Center,
Keck School of Medicine,
University of Southern California,
Los Angeles, CA 90033
Essential resource for clinical use and cancer research
A powerful tool that covers the entire spectrum of cancer biomarkers in development and clinical use
Explores predictive and prognostic markers
Written by international experts
Provides insight into toxicity and surrogate markers
Date de parution : 09-2012
Ouvrage de 447 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 158,24 €
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Mots-clés :
Biomarker; Breast; Cancer; Colon; Drug Development; Lung; Microassay; Oncology; Predictive; Prognostic; Prostate; Surrogate; Toxicity