Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease, Softcover reprint of the original 1st ed. 2015 Current Topics in Behavioral Neurosciences Series, Vol. 22
Coordonnateurs : Nguyen Hoa Huu Phuc, Cenci M. Angela
Clinical Aspects of Huntington’s Disease.- The Neuropathology of Huntington’s Disease.- Neurobiology of Huntington’s Disease.- Mouse Models of Huntington’s Disease.- Transgenic Rat Models of Huntington’s Disease.- Large Animal Models of Huntington’s Disease.- Therapeutic Strategies for Huntington’s Disease.- Clinical and Pathological Features of Parkinson’s Disease.- Symptomatic Models of Parkinson’s Disease and L-DOPA-Induced Dyskinesia in Non-human Primates.- Neuroinflammation in Parkinson’s Disease Animal Models: A Cell Stress Response or a Step in Neurodegeneration?.- Viral Vector-Based Models of Parkinson’s Disease.- Transgenic Rodent Models to Study Alpha-Synuclein Pathogenesis, with a Focus on Cognitive Deficits.- Modeling LRRK2 Pathobiology in Parkinson’s Disease: From Yeast to Rodents.- Models of Multiple System Atrophy.
Gives an overview of the clinical aspects of Huntington’s Disease (HD) and Parkinson’s Disease (PD) and reviews the construct, face and predictive validity of animal models
Provides information on which model to choose for specific research questions and on how they can be used for therapeutic target validation and treatment trials
Written by renowned researchers in the field
Includes supplementary material: sn.pub/extras
Date de parution : 10-2016
Ouvrage de 397 p.
15.5x23.5 cm
Date de parution : 06-2015
Ouvrage de 397 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 105,49 €
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Mots-clés :
Huntington; LRRK2; Parkin; Pink-1; Polyglutamine; animal models