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B Cells in Immunity and Tolerance, 1st ed. 2020 Advances in Experimental Medicine and Biology Series, Vol. 1254

Langue : Anglais

Coordonnateur : Wang Ji-Yang

Couverture de l’ouvrage B Cells in Immunity and Tolerance

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.

B cell development and maturation.- B cell receptor signalling.- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger.- Germinal center reaction.- Memory B cells in local and systemic sites.- Regulation of plasma cell differentiation.- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor.- Regulatory B cells.- Diversified IgA-bacteria interaction in gut homeostasis.- Primary antibody deficiencies.- B cell-mediated autoimmune diseases.- B cell lymphomas.

Dr. Ji-Yang Wang is a professor at Department of Immunology, School of Basic Medical Sciences, Fudan University, China. He was recruited to the 1000Talents Program of Shanghai in 2013. Prof. Wang’s research focuses on B cell development, activation and differentiation, and B cell-related diseases. He has published more than 100 articles on international journals in these fields.

Providing with the cutting-edge developments in all aspects of B cell biology Covering human B cell related diseases Serving as a routine and standard reference for both basic researchers and clinicians

Date de parution :

Ouvrage de 181 p.

17.8x25.4 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

158,24 €

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Date de parution :

Ouvrage de 181 p.

17.8x25.4 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

158,24 €

Ajouter au panier