Part I. Pathophysiology of Acquired Aplastic Anemia: 1. Stem cell defect in aplastic anemia J. C. W. Marsh and N. G. Testa, 2. Cytokine abnormalities in aplastic anemia S. Kojima, 3. Role of T-lymphocytes and apoptosis in pathophysiology of aplastic anemia S. Nakao, 4. Role of apoptosis in pathophysiology of aplastic anemia F. M. Gibson, N. J. Philpott, J. C. W. Marsh and E. C. Gordon-Smith, 5. Interrelation between aplastic anemia and paroxysmal nocturnal hemoglobinuria G. Socié, J.-Y. Mary, H. Schrezenmeier and E. Gluckman, 6. Aplastic anemia and other clonal disorders A. Raghavachar, Part II. Epidemiology and Clinical Features of Acquired Aplastic Anemia: 7. Epidemiology and etiology of aplastic anemia H. Heimpel, 8. Clinical presentation, natural course and prognostic factors P. Marin-Fernandez, Part III. Treatment of Acquired Aplastic Anemia: 9. Supportive treatment of patients with severe aplastic anemia P. Ljungman, 10. Immunosuppressive treatment of aplastic anemia A. Bacigalupo, H. Schrezenmeier and A. Tichelli, 11. Role of cytokines in the treatment of aplastic anemia H. Schrezenmeier, 12. HLA-identical sibling bone marrow transplantation to treat severe aplastic anemia S. R. McCann, J. R. Passweg, R. Storb and H. J. Deeg, 13. Alternative donor bone marrow transplantation for severe acquired aplastic anemia J. M. Hows, J. V. Stone and B. M. Camitta, 14. Treatment of children with acquired aplastic anemia A. Locasciulli, 15. Long-term follow up of patients with aplastic anemia A. Tichelli and G. Socié, 16. Guidelines for treatment of aplastic anemia (international consensus document), Part IV. Fanconi's Anemia: 17. Clinical features and diagnosis of Fanconi's anemia B. P. Alter, 18. Genetic basis of Fanconi's anemia M. Buchwald and M. Carreau, 19. Treatment of Fanconi's anemia E. Gluckman, G. Socié and P. Guardiola, 20. Genetic correction of Fanconi's anemia J. M. Liu.