Advances in Ceramic Biomaterials Materials, Devices and Challenges
Coordonnateurs : Palmero Paola, De Barra Eamonn, Cambier Francis
Bioceramics are an important class of biomaterials. Due to their desirable attributes such as biocompatibility and osseointegration, as well as their similarity in structure to bone and teeth, ceramic biomaterials have been successfully used in hard tissue applications. In this book, a team of materials research scientists, engineers, and clinicians bridge the gap between materials science and clinical commercialization providing integrated coverage of bioceramics, their applications and challenges.
The book is divided into three parts. The first part is a review of classes of medical-grade ceramic materials, their synthesis and processing as well as methods of property assessment. The second part contains a review of ceramic medical products and devices developed, their evolution, their clinical applications and some of the lessons learned from decades of clinical use. The third part outlines the challenges to improve performance and the directions that novel approaches and advanced technologies are taking, to meet these challenges.
With a focus on the dialogue between surgeons, engineers, material scientists, and biologists, this book is a valuable resource for researchers and engineers working toward long-lasting, reliable, customized biomedical ceramic and composites devices.
Part I: An overview of bio-medical grade ceramic materials 1. Materials for Hard Tissue applications: an overview 2. Types of ceramics: material class 3. Assessment of mechanical properties of ceramic materials 4. Biological assessment of bioceramics
Part II: Bioceramics on the market: issues and perspectives 5. Ceramics for joint replacement: design and application of commercial bearings 6. Ceramics for dentistry: commercial devices and their clinical analysis 7. Ceramics for bone replacement: commercial products and clinical use 8. Ceramic devices for bone regeneration. Mechanical and clinical issues and new perspectives 9. Clinical issues of ceramic devices used in total hip arthroplasty
Part III: Engineering and challenges of new ceramics for medical devices 10. Design of ceramic materials for orthopaedic devices 11. Design and development of dental ceramics: examples of current innovations and future concepts 12. Patient-specific design of tissue engineering scaffolds, based on mathematical modeling 13. Tissue Engineering and biomimetics with bioceramics 14. Advanced processing techniques for customized ceramic medical devices
materials scientists, clinical researchers and engineers, R&D staff in industry
current largest European network on biomaterials, and she has an active participation to FP6, FP7, and H2020 European projects. Her scientific production counts on over 90 papers, 6 patents, and numerous invited talks in international conferences.
Eamonn De Barra is a materials scientist with over twenty years’ experience in the development and commercialisation of a range of biomaterials and medical devices for dental and orthopaedic applications. With experience of biomaterials from development to translation, Dr. de Barra has previously developed and commercialised a complete product range of dental materials; developed, manufactured and marketed 6 novel precious metal alloys for prosthodontic applications, as well as developing a commercial bioactive bone cement for Ossicular Chain Reconstruction and an injectable bone substitute for Craniotomy Defect Closure. His current research interest is focused on purely commercial orthopaedic materials development, leading a range of research projects based on developing new orthopaedic implantable materials and tailoring their properties in order to optimise their in-vitro and in-vivo performance, as well as the handling and performance requirements dictated by defined user and clinical needs.
Francis Cambier is director General of the Belgium Ceramic Research Centre (BCRC), closely linked with the Belgian Ceramic Industry Association and the INISMa, a joint institute with the University of Mons. With over 30 years’ experience in the field, Dr Cambier is in
- Edited by a team of experts with expertise in industry and academia
- Compiles the most relevant aspects on regulatory issues, standards and engineering of bioceramic medical devices as inspired by commercial and clinical needs
- Introduces bioceramics, their evolution and applications in hard tissue engineering and medical devices
Date de parution : 10-2017
Ouvrage de 500 p.
15x22.8 cm
Thèmes d’Advances in Ceramic Biomaterials :
Mots-clés :
3D cell culture; 3D printing; ATZ; Aging; Alumina; Apatitic bone cements; Bio-inspired structures; Bioactive glass; Bioactive glass and calcium phosphates; Bioactive glasses; Bioactive oxides; Biocements; Bioceramic; Bioceramics; Biocompatibility; Bioglasses and bioglass ceramics; Bioinert and biodegradable ceramics; Bioinert ceramics; Biomimetic materials; Biomineralization; Biomorphic transformations; Bioreactors; Bone cement; Bone healing; Bone regeneration; Bone tissue engineering; CAD/CAM; Calcium phosphate; Calcium phosphates; Ceramic; Ceramic materials; Ceramic post; Ceramics for orthopedics; Coatings; Composites; DLC; Dental ceramics; Dental devices; Dentistry; Digital ceramics; Drug delivery devices; Failure analysis; Freeze-casting; Glass ceramics; Glass-ionomer cements; Hierarchically organized scaffolds; Hip replacement; Hybrid scaffold; Hydroxyapatite; Implant abutments; In vitro models; In vivo models; Ion-doped apatites; Joint replacement; Knee replacement; Lifetime; Magnetic biomaterials; Material design; Mechanical properties; New developments; Nitrides; Orthopedic devices; Orthopedics; Oxide and nonoxide ceramics; Porous scaffolds; Preclinical models; R-curve; Reliability; Scaffold design; Scaffolds; Selective laser sintering; Shaping; Shoulder replacement; Slow crack growth; Slurry extrusion; Stereolithography; Structural inert ceramics; THA; Tissue engineering; Toughness; ZTA; Zirconia; Zirconia-based composites; Zirconia-toughened alumina