Acromegaly: 130 Years Later Special Topic Issue: Neuroendocrinology 2016, Vol. 103, No. 1

In 1886, Pierre Marie coined the term 'acromegaly'. Since then, understanding of the disorder has improved and knowledge of genetics and treatment has been substantially developed. Despite significant advances, limitations still exist. Acromegaly: 130 Years Later contains clinical reviews by key opinion leaders. Papers cover such topics as the efficacy and safety of various medical treatments, technical advances in pituitary surgery, and radiotherapy. Morbidities and mortality markers are discussed, including the possibility that treatment modalities cause morbidity. The effects of associated diseases such as bone and joint disorders, cardiovascular disease, and sleep disorders are also highlighted. Besides the classical clinical reviews, there is a translational review on glucose and lipid metabolism as well as a practical, but also molecular review on MEN syndromes and carneys complex. This issue of Neuroendocrinology is a valuable resource for every acromegaly specialist who must choose the optimal treatment for, and provide essential advice to, their patients.