Bioactive Materials for Bone Regeneration

Langue : Anglais

Auteurs : Chang Jiang, Zhang Xingdong, Dai Kerong

Couverture de l’ouvrage Bioactive Materials for Bone Regeneration

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Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration.

1. Characteristics, surface/interface and biological effects on osteogenesis of bioactive materials 2. Biomaterial-induced microenvironment and host reaction in bone regeneration 3. Bone regeneration concept based on immune microenvironment regulation

Undergraduate and graduate students and practitioners in biomedical engineering, life and biological sciences, materials, mechanical and engineering sciences, and medicine.

Jiang Chang is a professor at the Shanghai Institute of Ceramics, Chinese Academy of Sciences, China, and an Associate of the University of Manitoba Transport Institute. He is one of the leading young scholars worldwide in the field of transport economics and policy in the sectors of aviation, rail and maritime. He has received numerous prestigious accolades such as the Associates’ Achievement Award for Outstanding Business Research. His research focuses on bioactive materials for tissue regeneration and tissue engineering and the mechanisms of the interaction between biomaterials and cells. Professor Chang has over 300 scientific papers published in international peer-reviewed scientific journals and 70 patents in the field of biomedical materials.
Xingdong Zhang is a professor of Sichuan University, and President of the International Union of Societies for Biomaterials Science and Engineering (IUSBSE), and Honorary President of the Chinese Society for Biomaterials (CSBM). His research focuses on calcium-phosphate biomaterials and implantable medical devices for musculoskeletal system. In 1983, he was the first in China to research and develop hydroxyapatite (HA) ceramics and related synthetic bone grafts. In 1987, he was the first in China to design and develop titanium dental implants and total hip replacements (THR) with plasma-sprayed hydroxyapatite (HA) coatings. He was one of the pioneers in the world to find and confirm that porous calcium phosphates ceramics can induce bone formation in 1991. To date, three companies founded by him have obtained six Registration Certificates for Medical Devices issued by the China Food and Drug Administration. 20 series of products with over 200 different specifications have been commercialized and applied to dozens of thousand cases in near 1000 Chinese hospitals. Prof. Zhang has made significant contributions to the development of biomaterials science and engineering in China and the world. As one of the major partici

Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications
Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration
Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments