Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions (4th Ed., 4th ed. 2018) Infectious Disease Series
The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes ? ?Mechanisms and Models of Drug Interactions? and ?Antimicrobial Drug Interactions?.
This volume, ?Mechanisms and Models of Drug Interactions,? delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.
Introduction to Drug-Drug Interactions.- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion.- Mechanisms of Drug Interactions II: Transport Proteins.- Drug-Food Interactions.- Drug-Cytokine Interactions.- Interactions between Herbs and Antiinfective Medications.- In vitroModeling of Drug-Drug Interactions.- Probe Cocktail Studies.- Design and Data Analysis in Drug Interaction Studies.
Manjunath P. Pai, College of Pharmacy, University of Michigan, Ann Arbor, MI
Jennifer J. Kiser, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO
Paul O. Gubbins, School of Pharmacy, University of Missouri-Kansas City, Springfield, MO
Keith A. Rodvold, University of Illinois, College of Pharmacy and Medicine, Chicago, ILA definitive resource on food-drug and herb-drug interactions
Brand new chapter on in vitro modeling of drug interactions
Fills a gap in the medical literature on the complex relations between acute infection, inflammation, and the risk of drug interactions
Date de parution : 02-2019
Ouvrage de 326 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 121,31 €
Ajouter au panierDate de parution : 03-2018
Ouvrage de 326 p.
15.5x23.5 cm
Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).
Prix indicatif 121,31 €
Ajouter au panierThème de Drug Interactions in Infectious Diseases: Mechanisms and... :
Mots-clés :
infectious disease; drug interactions; HIV; HCV; antimicrobials; infectious diseases