Bone Regulators and Osteoporosis Therapy, 1st ed. 2020 Handbook of Experimental Pharmacology Series, Vol. 262

This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the  cells of bone and their interactions.  Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments. 

Provides an understanding of the mechanisms by which multiple factors and therapeutic agents affect bones

Gives an overview of the genetics of bone disorders and discusses the pathophysiology of osteoporosis

Maximizes insights in current and potential osteoporosis therapies and treatments