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Adhesion in Pharmaceutical, Biomedical, and Dental Fields Adhesion and Adhesives: Fundamental and Applied Aspects Series

Langue : Anglais

Coordonnateurs : Mittal K. L., Etzler F. M.

Couverture de l’ouvrage Adhesion in Pharmaceutical, Biomedical, and Dental Fields
The phenomenon of adhesion is of cardinal importance in the pharmaceutical, biomedical and dental fields. A few eclectic examples will suffice  to underscore the importance/relevance of adhesion in these three areas. For example, the adhesion between powdered solids is of crucial importance in tablet manufacture. The interaction between biodevices (e.g., stents, bio-implants) and body environment dictates the performance of such devices, and there is burgeoning research activity in modifying the surfaces of such implements to render them compatible with bodily components. In the field of dentistry, the modern trend is to shift from retaining of restorative materials by mechanical interlocking to adhesive bonding.

This unique book addresses all these three areas in an easily accessible single source. The book contains 15 chapters written by leading experts and is divided into four parts: General Topics; Adhesion in Pharmaceutical Field; Adhesion in Biomedical Field; and Adhesion in Dental Field.

The topics covered include:
- Theories or mechanisms of adhesion.
- Wettability of powders.
- Role of surface free energy in tablet strength and powder flow behavior.
- Mucoadhesive polymers for drug delivery systems.
- Transdermal patches.
- Skin adhesion in long-wear cosmetics. 
- Factors affecting microbial adhesion. 
- Biofouling and ways to mitigate it. 
Preface

Part 1 - General Topics

1. Theories and Mechanisms of Adhesion in the Pharmaceutical, Biomedical and Dental Fields
. 1.1 Introduction
. 1.2 Mechanisms of Adhesion
. 1.3 Summary
. References
2. Wettability of Powders
. 2.1 Introduction
. 2.2 Different Forms of Wetting
. 2.3 Hydrophilic and Hydrophobic Surfaces
. 2.4 Contact Angle Measurement in Wettability Studies of  Powdered Materials
. 2.5 Contact Angle and Surface Free Energy
. 2.6 Surface Free Energy Determination of Powdered Solids by Thin Layer Wicking Method
. 2.7 Surface Free Energy Determination of Powdered Solids by Imbibition Drainage Method
. 2.8 Summary
. Acknowledgement
. References

Part 2 - Adhesion in the Pharmaceutical Field

3. Tablet Tensile Strength: Role of Surface Free Energy
. 3.1 Introduction
. 3.2 Applicability of the Proposed Model to Pharmaceutical Materials
. 3.3 Discussion
. 3.4 Summary
. 3.5 Acknowledgements
. References
4. Role of Surface Free Energy in Powder Behavior and Tablet Strength
. 4.1 Introduction
. 4.2 Surface Free Energy
. 4.3 Role of Surface Free Energy in Solid Wetting
. 4.4 Role of Surface Free Energy in Powder Flow
. 4.5 Role of Surface Free Energy in Powder Tableting
. 4.6 Concluding Remarks
. References
5. Mucoadhesive Polymers for Drug Delivery Systems
. 5.1 Introduction
. 5.2 Mucoadhesive Drug Delivery Systems
. 5.4 Summary
. References
6. Transdermal Patches: An Overview
. 6.1 Introduction
. 6.2 Factors Affecting Skin Absorption
. 6.3 Passive Transdermal Drug Delivery Systems
. 6.4 Types, Structural Components and Materials Used to Design Passive TDDS
. 6.5 Active Transdermal Drug Delivery Systems
. 6.6 Production of Transdermal Patches
. 6.7 Biopharmaceutical Concerns
. 6.8 Pharmacokinetics of Transdermal Absorption
. 6.9 Manufacture, Design and Quality Control
. 6.10 Commercialized Patches
. 6.11 Regulatory Aspects
. 6.12 Summary and Future Prospects
. Acknowledgment
. References
7. Film-Forming Technology and Skin Adhesion in Long-Wear Cosmetics
. 7.1 Introduction
. 7.2 Long-Wear Foundation: An overview
. 7.3 Effect of Skin Substrate on Adhesion
. 7.4 Long-Wear Technologies in Cosmetic Applications
. 7.5 Summary and Prospects
. Acknowledgements
. References

Part 3 - Adhesion in the Biomedical Fields

8. Factors Affecting Microbial Adhesion
. 8.1 Introduction
. 8.2 Surface Characterization
. 8.3 Bacterial Adhesion to Material Surfaces
. 8.5 Summary
. Acknowledgments
. References
9. Factors Influencing Biofouling and Use of Polymeric Materials to Mitigate It
. 9.1 Introduction
. 9.2 Origin of Biofouling
. 9.3 Prevention of Microorganisms Adhesion
. 9.4 Influence of Mechanical Properties
. 9.5 Influence of Surface Topography
. 9.6 Concluding Remarks
. References
10. Coatings on Surgical Tools and How to Promote Adhesion of Bio-Friendly Coatings on Their Surfaces
. 10.1 Introduction
. 10.2 Coatings on Various Surgical Tools and Implants in Different Fields of Operative Care to Patients
. 10.3 Promotion of Adhesion of Bio-Friendly Coatings on Surfaces of Tools and Implants
. 10.4 Summary
. References
11. Techniques for Deposition of Coatings with Enhanced Adhesion to Bio-Implants
. 11.1 Bio-Implants: An Introduction
. 11.2 Deposition Methods for Enhanced Adhesion of Coatings on Implants
. 11.3 Summary
. References
12. Relevance of Adhesion in Fabrication of Microarrays in Clinical Diagnostics
. 12.1 Introduction
. 12.2 Protein Microarrays
. 12.3 Fabrication Techniques
. 12.4 Adhesion of Probes in Protein Microarray Fabrication
. 12.6 Antibody Microarrays
. 12.7 Summary
. References

Part 4 - Adhesion in the Dental Fields

13. Antibacterial Polymers for Dental Adhesives and Composites
. 13.1 Introduction
. 13.2 Major Damage from Oral Biofilm Formed: The Acid Production
. 13.3 The Chemistry of Current Dental Adhesives and Composites
. 13.4 The Need for Treatments Targeting Oral Cariogenic Biofilms
. 13.5 Classification of Antibacterial Polymers for Dental Materials
. 13.6 Mechanisms of Action of Antibacterial Monomers
. 13.7 Antibacterial Properties of Dental Adhesives and Composites Containing Antibacterial Monomers
. 13.8 Considerations of Mechanical Properties
. 13.9 Summary and Prospects
. Acknowledgments
. References
14. Dental Adhesives: From Earlier Products to Bioactive and Smart Materials
. 14.1 Introduction
. 14.2 Adhesion to Dental Substrates
. 14.3 Adhesive Strategies
. 14.4 Limitations in Bonding to Dental Substrates
. 14.5 Strategies to Reduce Bond Strength Degradation – Current Advances
. 14.6 Summary and Prospects
. Acknowledgment
. References
15. Testing of Dental Adhesive Joints 
. 15.1 Introduction
. 15.2 Various Bond Strength Tests
. 15.3 Summary
. References
Kashmiri Lal Mittal was employed by the IBM Corporation from 1972 through 1993 Currently, he is teaching and consulting worldwide in the broad areas of adhesion as well as surface cleaning. He is the editor of more than 135 books and the Founding Editor of the journal Reviews of Adhesion and Adhesives.
Frank Etzler earned his PhD in physical chemistry from the University of Miami. He is currently an Associate Professor of Pharmaceutics in the School of Pharmacy at the Lake Erie College of Osteopathic Medicine (LECOM).

Date de parution :

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15.9x23.3 cm

Disponible chez l'éditeur (délai d'approvisionnement : 12 jours).

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Thèmes d’Adhesion in Pharmaceutical, Biomedical, and Dental Fields :

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