Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids

Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids includes comprehensive coverage of name reactions in the synthesis of alkaloids. This book highlights the synthesis of various alkaloids using special name reactions including the Diels-Alder, Friedel-Crafts, Heck, Mannich, Pauson-Khand, Pictet-Spengler, Sonogashira and Suzuki reactions.

In this book, some selected name reactions in the total synthesis of alkaloids are covered, as they can be used as the key step/steps in the synthesis of different alkaloids exhibiting various biological activities. All chapters include an introduction, history and mechanism of the name reaction, and present the origin of the natural product and its known biological activities. The pathway to total synthesis is visually illustrated, and the focus is on the step in which a name reaction is applied. Chemists working in the area of synthetic organic chemistry will find this reference useful, as well as those working to develop novel methodologies for the synthesis of natural products in both academia and industry. This book is also beneficial to biologists, pharmacists and botanists.

1. Applications of selected name reactions in total synthesis of alkaloids 2. Applications of DielseAlder cycloaddition reaction in total synthesis of alkaloids 3. Recent advances in applications of FriedeleCrafts reactions in total synthesis of alkaloids 4. Recent advances in applications of Heck reaction in the total synthesis of alkaloids 5. Recent advances in applications of Mannich reaction in total synthesis of alkaloids 6. Applications of PausoneKhand reaction in the total synthesis of alkaloids 7. Applications of PicteteSpengler reaction in the total synthesis of alkaloids 8. Applications of the Sonogashira reaction in the total synthesis of alkaloids 9. Recent advances in applications of Suzuki reaction in the total synthesis of alkaloids

Chemists working in the area of synthetic organic chemistry, developing new/novel methodologies for the synthesis of natural products in academia as well as industries. It is especially useful for those groups working in drug design and drug discovery.

• Includes an introduction of alkaloids, their origins and biological properties
• Features the applications of special name reactions as the key step in the total synthesis of featured alkaloids
• Covers the pathway for the synthesis of alkaloids from commercially available or easily accessible starting materials by using at least one name reaction to achieve the desired target products