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Ion mobility spectrometry (3rd Ed.)

Langue : Anglais

Auteurs :

Couverture de l’ouvrage Ion mobility spectrometry
Beginning with a thorough discussion of the fundamental theories and physics of ion mobility, this third edition reference follows the traditional organization of the original, beginning with fundamental theories and physics of ion mobility. It then moves on to the recent advances in instrumentation and newly pioneered applications. Each chapter is thoroughly updated, with new information on present trends in IMS and coverage of FAIMS and DMS/MS. Significant expansion to the Biological and Biomedical section is provided, with an emphasis on LC ESI Mobility MS or ESI Mobility MS, including IMS TOF. The previously included CD-ROM is now available as a webpage for qualified instructors.

Introduction to Ion Mobility Spectrometry
Methods of Ion Mobility Spectrometry
Emerging Patterns in the Development of Ion Mobility Methods Summary Comments

History of Ion Mobility Spectrometry
The Formative Years of Discovery (1895 to 1960)
Ion Mobility Spectrometry for Chemical Measurements (1960 to 1990)
Mobility Methods beyond Military and Security Venues (1990 to 2000)
Commercial Production of Mobility-Based Analyzers (2000 to Present)
The Society for Ion Mobility Spectrometry and Journal

Sample Introduction Methods
Vapor Samples
Semi-volatile Samples
Aqueous Samples
Solid Samples

Ion Sources
Radioactivity: Nickel, Americium, and Tritium
Corona Discharges
Photo-ionization: Discharge Lamps and Lasers
Electrospray Ionization and Its Derivatives
Matrix-Assisted Laser Desorption Ionization
Surface Ionization Sources
Plasma-Based Ion Sources
Glow Discharge Ion Source
Other Ion Sources

Ion Injection and Pulsed Sources
Operation and Structures of Ion Shutters
Models and Modes of Operation
Ion Injection to Drift Regions without Wire-Based Ion Shutters
Mobility Methods with Continuous Flow of Ions into the Drift Region
Summary and Conclusions

Drift Tubes in Ion Mobility Spectrometry
Traditional Drift Tubes with Stacked-Ring Designs
High Field Asymmetric Drift Tubes
Aspirator Drift Tubes
Traveling Wave Drift Tubes
Tandem Mobility Spectrometers
Other Drift Tube Designs
Selection of Materials
Summary and Conclusions

Ion Detectors
Ambient Detection of Mobility-Separated Ions
Low-Pressure Detection of Mobility-Separated Ions

The Ion Mobility Spectrum
Mobility, Electric Field, and Pressure
Ion Mobility Spectra
IMS as a Separation Device
Quantitative Aspects to Response

Ion Mobility-Mass Spectrometry
Combining Mobility with Mass
Low-Pressure Drift Tube Ion Mobility Spectrometry-Mass Spectrometry Atmospheric Pressure Drift Tube Ion Mobility Mass Spectrometry Differential Mobility Spectrometry-Mass Spectrometry
Aspiration Ion Mobility Spectrometry-Mass Spectrometry
Ion Mobility MS and the Future

Ion Characterization and Separation: Mobility of Gas Phase Ions in Electric Fields
Motion of Slow Ions in Gases
Models for Ion-Neutral Interactions
Linear Ion Mobility Spectrometers: Models and Experimental Evidence
Differential Mobility Spectrometer and the Dependence of Ion Mobility on the Electric Field Strength
Traveling Wave IMS

Control and Effects of Experimental Parameters
Chemical Composition of the Support Gas Atmosphere
Moisture and Temperature of the Supporting Gas Atmosphere
Effects of Pressure
Effects of Field Strength and Ion Residence Time
Effects of Analyte Concentration

Detection of Explosives by IMS
General Comments on Detection of Explosives
The Chemistry Underlying Detection of Explosives by IMS
Sampling and Pre-concentration Techniques for Detection of Explosives
Measurement with Handheld Devices, Portable Instruments, and Portals
Research and Operational Experience
Walk-Through Portals and Systems for Luggage Screening
Homemade and Alternate Explosives
Standards for Calibration of Explosive Detectors
Database for Explosives

Chemical Weapons
Introduction and General Comments on Detection of Chemical Warfare Agents
The Ion Chemistry Underlying Detection of Chemical Weapons
Sampling and Pre-concentration Techniques
Research, Operational Experience, and Historical Perspective of Instrumentation
State-of-the-Art Commercial Instruments, Standards, and Calibration

Drugs of Abuse
Introduction and General Comments on Detection of Drugs
The Ion Chemistry Underlying Detection of Drugs
Sampling and Pre-concentration Techniques
Research, Operational Experience, and Instrumentation
Standards and Calibration
Database for Drugs

Compound Identification
Formulation Validation
Cleaning Validation
Reaction Monitoring
Monitoring Biological Samples
Summary and Conclusion

Industrial Applications
Industrial Processes
Industrial Feedstock or Products
Food Production

Environmental Monitoring
Airborne Vapors

Biological and Medical Applications of IMS
Introduction and General Comments on Biological and Medical Applications
Medical Diagnostics Using IMS
Food Freshness, Molds, and Odor Detection
Macromolecules: Biomolecules and Biopolymers
Detection and Determination of Bacteria
Other Biological Applications

Current Assessments and Future Developments in Ion Mobility Spectrometry
State of the Science and Technology of IMS
Next Generation in Ion Mobility Methods
Directions for IMS
Final Thoughts

Analytical chemists working with IMS within the fields of biological, biomedical, clinical, forensic, environmental sciences, and industrial detection and monitoring.

Date de parution :

15.6x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 13 jours).

Prix indicatif 80,69 €

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Date de parution :

Ouvrage de 500 p.

15.6x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 13 jours).

Prix indicatif 161,06 €

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Thème d’Ion mobility spectrometry :

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