Translating Epigenetics to the Clinic
Coordonnateur : Laurence Jeffrey
Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ?diseases of modernity??including pharmacological addiction, dementia, and ageing.
Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. The book promotes cross-disciplinary communication between the sub-specialties of medicine. In common with the rest of the books in Translational Medicine, the book remains unified in theme by emphasizing recent innovations, critical barriers to progress, and the new tools being used to overcome them. Also includes specific areas of research that require additional study to advance the field as a whole.
- Encompasses the latest innovations and tools being used to apply epigenetics in the lab and clinic
- Features extensive pedagogical updates aiming to improve the education of translational researchers in this field
- Offers a transdisciplinary approach to support cross-fertilization between different sub-specialties of medicine
Date de parution : 01-2017
Ouvrage de 324 p.
15x22.8 cm
Thème de Translating Epigenetics to the Clinic :
Mots-clés :
Aging; Alzheimer's disease; Anxiety; Arterial hypertension; Atherosclerosis; COPD; Cancer; Cardiovascular; Cardiovascular diseases; Cell differentiation; Chromatin; Chromatin remodeling; Chromatin states; Clinical translation; DNA damage repair; DNA demethylation; DNA methylation; Development; Disease; Dorsal root ganglion; Embryonic development; Embryonic stem cell; Epigenetic mechanisms; Epigenetics; Epigenomics; Evolution; Fibromyalgia; Gene expression; Genetics; HAT; HDAC; Heart failure; Histone; Histone acetylation; Histone hyperacetylation; Histone methylation; Histone modification; Histone modifications; Inflammatory pain; Irritable bowel syndrome; M6A; Methylation; MicroRNA; MicroRNAs; Multifactorial etiology; Muscle dysfunction and mass loss; N6-methyladenosine; NSCLC; Neuropathic pain; Noncoding RNA; NuRD complex; Opioid tolerance; Opioid-induced hypersensitivity; Pluripotency; Pluripotent stem cell; RNA epigenetics; RNA modification; RNA-protein interaction; Rejuvenation; SCLC; Senescence; Small noncoding RNAs; Spinal cord; Visceral pain; Zebrafish