The Wiley-Blackwell Handbook of Addiction Psychopharmacology Wiley Clinical Psychology Handbooks Series

?Much of our scientific effort in tackling the multifactorial nature of addiction has taken place within individual disciplines. However, it has become increasingly clear that the complexity of addiction requires an integrated approach. This Handbook is timely and exceptional, intelligently combining the latest research approaches and applying them to understanding and tackling the prodigious public health burden of addiction. An authoritative resource, it establishes a comprehensive framework that will guide the field in the next era of addiction research.?

John F. Kelly, PhD, President Elect, Society of Addiction Psychology, American Psychological Association; Associate Professor in Psychiatry, Harvard Medical School; Director, Addiction Recovery Management Service, Massachusetts General Hospital

The Wiley-Blackwell Handbook of Addiction Psychopharmacology presents a comprehensive guide to contemporary research approaches to the study of drug addiction in adults. With a focus on empirically relevant research methods and nuanced methodologies, it provides practical tools to enable strong psychopharmacological practices. Contributions from experts in diverse domains offer reviews of the most current experimental methodologies, make recommendations for ?best practices,? and identify future directions for the field. Topics covered include core methods for assessing drug effects, distal and proximal determinants of drug use, and insights from cognitive neuroscience.

Compiled by a team of widely published researchers in substance addiction, The Wiley-Blackwell Handbook of Addiction Psychopharmacology is an authoritative, state-of-the-art collection of modern research approaches to the scientific study of drug addiction. Its multidisciplinary approach makes it a comprehensive and invaluable resource for all those in this field.

About the Editors xi

About the Contributors xiii

Introduction: The Science of Addiction Psychopharmacology 1
James MacKillop & Harriet de Wit

Part I Distal Determinants of Drug Use 5

1 Developmental Factors in Addiction: Methodological Considerations 7
Laurie Chassin, Clark Presson, Young Il-Cho, Matthew Lee, and Jonathan Macy

2 Executive Dysfunction in Addiction 27
David P. Jarmolowicz, E. Terry Mueller, Mikhail N. Koffarnus, Anne E. Carter, Kirstin M. Gatchalian, and Warren K. Bickel

3 The Roles of Race and Sex in Addiction Research 63
Ezemenari M. Obasi, Jaime L. Richards, Delishia M. Pittman, Jokae Ingram, Marian R. Beasley, and Kristen L. Ratliff

4 Understanding Psychiatric Comorbidities and Addictions 83
James C. (Jim) Anthony

5 Personality and Addiction: A Critical Review of Assessment Approaches 111
Joshua D. Miller and Donald R. Lynam

6 Behavioral Inhibition and Addiction 135
Mark T. Fillmore and Jessica Weafer

7 Delay Discounting and Drug Abuse: Empirical, Conceptual, and Methodological Considerations 165
Jeffrey S. Stein and Gregory J. Madden

8 Assessment of Risk Taking in Addiction Research 209
Jennifer Dahne, Jessica M. Richards, Monique Ernst, Laura MacPherson, and Carl W. Lejuez

9 Distress Tolerance 233
Jessica F. Magidson, Bina Ali, Alyson Listhaus, and Stacey B. Daughters

Part II Proximal Determinants of Drug Use 257

10 Measuring Direct Effects of Drugs of Abuse in Humans 259
Harriet de Wit

11 The Role of Aftereffects and Withdrawal in Addiction 281
Jon D. Kassel, Jennifer C. Veilleux, Adrienne J. Heinz, Ashley Braun, and Stefanie Weber

12 Drug Self-Administration Paradigms: Methods for Quantifying Motivation in Experimental Research 315
James MacKillop and Cara Murphy

13 The Assessment of Craving in Addiction Research 345
Lara A. Ray, Kelly E. Courtney, Guadalupe Bacio, and James MacKillop

14 The Cue Reactivity Paradigm in Addiction Research 381
Elizabeth K. Reynolds and Peter M. Monti

15 Stress and Affective Inductions in Addiction Research 411
Suzanne Thomas and Amy Bacon

16 Substance Priming 435
Abigail K. Rose

17 Understanding the Role of Substance Expectancies in Addiction 459
Jane Metrik and Damaris J. Rohsenow

18 Implicit Cognition 489
Paul Christiansen and Matt Field

19 Experimental Methods for Understanding the Role of Social Context in Drug Addiction 515
Matthew G. Kirkpatrick and Margaret C. Wardle

20 Ecological Momentary Assessment 541
Thomas R. Kirchner and Saul Shiffman

Part III Insights from Cognitive Science 567

21 Startle Reflex and Psychophysiology 569
Jeffrey C. Meehan and Robert Miranda, Jr

22 Using Quantitative EEG and EEG Tomography to Understand Drug Abuse: A Quantum Leap in New Methods and Benefits 599
David G. Gilbert and Herman A. Diggs

23 Functional Magnetic Resonance Imaging in Addiction Research 643
Lawrence H. Sweet, Michael T. Amlung, and James MacKillop

24 The Role of Positron Emission Imaging (PET) in Understanding Addiction 677
Dean F. Wong, James Robert Brasic, Emily Gean, and Ayon Nandi

25 Application of Magnetic Resonance Spectroscopic Imaging to Addiction Research 707
Sujung Yoon, In Kyoon Lyoo, and Perry F. Renshaw

Conclusions: Consilience as the Future of Addiction Psychopharmacology 751
James MacKillop & Harriet de Wit

Index 755

Plate section between 688 and 689

James MacKillop is Associate Professor of the Department of Psychology, University of Georgia and Adjunct Associate Professor of the Department of Behavioral and Social Sciences, Brown University. Dr MacKillop’s research has been supported by the National Institutes of Health, the Robert Wood Johnson Foundation, and the Alcoholic Medical Research Foundation, among other granting agencies, and he has published over 90 peer-reviewed articles and book chapters in this area.

Harriet de Wit is Professor of the Department of Psychiatry and Behavioral Neuroscience, University of Chicago. Dr de Wit has published over 200 empirical papers and is an editor of the journals Psychopharmacology and Alcoholism: Clinical and Experimental Research.