The Scientist's Guide to Cardiac Metabolism
Coordonnateurs : Schwarzer Michael, Doenst Torsten
The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism.
This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects.
The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease.
Chapter 2. Historical perspectives
Chapter 3. Basics in metabolically relevant biochemistry
Chapter 4. Metabolically relevant cell biology - Role of intracellular organelles for cardiac metabolism
Chapter 5. Metabolic Pathways and cycles – the heart of cardiac metabolism
Chapter 6. Principles in the regulation of cardiac metabolism
Chapter 7. Diurnal variation in cardiac metabolism
Chapter 8. Methods and Models to investigate cardiac metabolism
Chapter 9. Nutritional and environmental influence on cardiac metabolism
Chapter 10. Influence of ischemia, hypoxia and reperfusion
Chapter 11. Cardiac metabolism in hypertrophy and heart failure
Chapter 12. Cardiac metabolism during development
Chapter 13. Similarities and differences between cardiac metabolism and metabolism of different organs
Chapter 14. Cardiac metabolism – where is the link to clinical practice?
scientists, researchers, and newcomers in cardiac metabolism
Professor Doenst heads the Department of Cardiothoracic Surgery at the University Hospital in Jena, where he places emphasis on an internationally comparable clinical performance, with a focus in the field of minimally invasive and complex valve surgery and the surgical treatment of heart failure, including ventricular assist devices and heart - and lung transplantation.
- Provides a quick and comprehensive introduction into cardiac metabolism
- Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs
- Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function
- Includes historical perspectives that reference important investigators that have contributed to the development of the field
Date de parution : 11-2015
Ouvrage de 240 p.
19x23.3 cm
Mots-clés :
adenosine triphosphate; adenylate kinase; amino acid; anaerobic glycolysis; anaplerosis; animal model; autophagy; β-oxidation; cardiac disease; cardiac energetics; cardiac hypertrophy; cardiac imaging; cardiac metabolism; cell culture; cell death; cellular respiration; cellular uptake; circadian; circadian rhythm; citric acid cycle; clock; creatine kinase; development; diurnal variation; elderly; endoplasmic reticulum; enzyme activity; enzymes; exercise; fasting; fatty acid oxidation; fatty acids; fetus; flux; genetically modified mice; glucose; glycogen; glycolysis; Golgi apparatus; heart; heart failure; heart failure therapy; Heinrich Taegtmeyer; hexosamine biosynthesis pathway; history; homeostasis; hormones; hypoxia; infarction; ischemia; ischemia-reperfusion; ischemic preconditioning; ketone body; Krebs cycle; lactate; Langendorff model; long-chain fatty acid; mammalia; metabolic; metabolic cycle; metabolic modulators; metabolic pathway; metabolic remodeling; metabolic substrate; metabolism; Mitchell hypothesis; mitochondria; mitochondrial biogenesis; new born; oxidative stress; pentose-phosphate pathway; peroxisome; PGC1; phosphagen systems; phosphocreatine; phosphorylation; postconditioning; posttranslational modifications; PPAR; Randle cycle; reactive oxygen species; reperfusion; ribosomes; Richard John Bing; substrate; substrate utilization; transcription; triacylglycerol; tricarboxylic acid cycle; vesicles; western diet
