The Liver in Biology and Disease Liver Biology in Disease, Hepato - Biology in Disease Principles of Medical Biology Series

The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. With this intention in mind, a volume of this nature takes into account the close dependence of progress in the medical sciences on bioinformatics (gene and protein analysis) or more precisely, computational biology and of course, the Internet. In general, it follows the pattern of its predecessors.

1. The Intrahepatic Biliary Tree (J.M. Crawford); 2. Functional Heterogeneity of the Intrahepatic Cholangiocytes (G.D. LeSage, S.S. Glaser, H.Francis, J.Phinizy, G. Alpini); 3. The Actin Cytoskeleton in Liver Function (R.B. Doctor, M.Nichols); 4. Mechanisms of Bile Formation and Cholestasis (M.S. Anwer); 5. The Role of Bile Acids in the Modulation of Apoptosis (C.M.P. Rodrigues, R.E. Castro, C.J. Steer); 6. Growth Factors and the Liver (C.Selden); 7. Chemokine And Cytokine Regulation Of Liver Injury (K.J.Simpson, N.Henderson); 8. Drug Metabolism and Hepatotoxicity (J.M. Tredger); 9. Assembly and Secretion of Hepatic Very-Low-Density Lipoprotein (G.Gibbons); 10. Bilirubin Metabolism (P.L.M. Jansen, E.E.Bittar) r; 11. Clinical Biochemistry of the Liver (N.McIntyre); 12. Alcoholic Liver Disease (S.F. Stewart, C.P. Day); 13. Fulminant Hepatic Failure (W. Ng, I.D. Norton, D.B. Jones); 14. Primary Biliary Cirrhosis (J.Neuberger); 15. Chronic Active Hepatitis (I.G. McFarlane); 16. Hepatitis B Virus (F.F. Poordad); 17. Current Issues in Hepatitis B Vaccines (J.N. Zuckerman, A.J. Zuckerman); 18. The Molecular Virology of Hepatitis C Virus (T.L. Tellinghuisen, C.M.Rice); 19. The Role of the Hepatic Stellate Cell in Liver Fibrosis (T.J. Kendall, J.P. Iredale); 20. Orthotopic Liver Transplantation (G. Singh, P. Rajvanshi, S. Gupta); 21. Biological Principles and Novel Therapies in Liver Cell Transplantation (S. Gupta, M. Inada, V. Kumaran, B. Joseph); 22. Fluid Transport in the Gall Bladder (J. Svanvik, B.Nilsson)

Medical students, predoctoral or postdoctoral graduates, hepatologists, and hepatopathologists, internists, critical care physicians, and graduates in the allied health sciences and nursing.

*Chapters are illustrated with numerous figures and references are current*Clear, concise and accurate text about a large number of liver diseases*Describes the liver's histology, biochemistry, and pathology in molecular terms